Today’s coronavirus news: Australia’s ban on cruise ships ends; Easter Sunday marks a return to in-person worship for many

Today’s coronavirus news: Australia’s ban on cruise ships ends; Easter Sunday marks a return to in-person worship for many

The latest coronavirus news from Canada and around the world Sunday. This file will be updated throughout the day. Web links to longer stories if available.

5:53 p.m.: According to official state numbers, Connecticut has recorded 3,939 positive COVID-19 tests in the past week, most in a seven-day period since early March.

In reality, experts say the true number is larger. Maybe much larger.

At previous stages of the pandemic, the vast majority of positive COVID-19 results came from tests administered by medical professionals and then reported to the Department of Public Health. But now Connecticut residents can purchase a test at a pharmacy and take it in their living room with no requirement that they report positive results anywhere or confirm their results with a medical provider.

That is good news when it comes to convenient testing access but bad news when it comes to tracking results.

“We have to be mindful of the data we are receiving and not receiving,” said Dr. David Banach, hospital epidemiologist at UConn Health. “Relying on [cases] as a primary way to gauge what’s circulating in the community is not as applicable right now.”

A sign outside of Charter Oak Health Center, which is administering vaccines and boosters daily. (Jessica Hill / Special to the Courant)

Official COVID-19 case counts have always underrepresented the true spread of the disease to some degree — as not everyone who gets infected develops symptoms or seeks a test — but experts say this has become especially true during the at-home testing era. Dr. Scott Gottlieb, a former FDA commissioner who has advised Gov. Ned Lamont during the pandemic, said recently he thinks the U.S. is “dramatically undercounting” COVID-19 cases, particularly in the Northeast.

3:55 p.m.: Quebec is reporting a 28-patient jump in COVID-19 hospitalizations Sunday.

The government’s open data portal shows there are 2,159 people in hospital with the disease.

There are 101 patients listed in intensive care, a drop of four patients from Saturday.

According to the open data portal, two more deaths were attributed to the novel coronavirus, for a total of 14,614 since the pandemic began.

The data shows there have been 1,040 new infections confirmed by PCR testing on Saturday, which is limited to higher-risk groups.

People aged 70 and over account for more than 71 per cent of the overall hospitalizations; further details on COVID-19-related hospitalizations and vaccinations will be released Tuesday.

12:20 p.m.: For many U.S. Christians, this weekend marks the first time since 2019 that they will gather in person on Easter Sunday, a welcome chance to celebrate one of the year’s holiest days side by side with fellow congregants.

The pandemic erupted in the country in March 2020, just ahead of Easter, forcing many churches to resort to online or televised worship. Many continued to hold virtual services last spring after a deadly winter wave of the coronavirus and as vaccination campaigns were still ramping up. But this year more churches are opening their doors for Easter services with few COVID-19 restrictions, in line with broader societal trends.

Among them are Catholic parishes in the Archdiocese of Boston, which since last June has once again required most churchgoers to attend Mass in person — though those with health risks may still watch remotely, and pastors have been asked to make space for social distancing in churches.

MC Sullivan, chief health care ethicist for the archdiocese, said celebrating Mass communally is important to how Catholics profess their faith. Church attendance has been trending upward, and parishioners are excited to gather again to commemorate Christ’s resurrection.

“It has been quite wonderful to see how well-attended Mass is right now. … It seems to have brought a lot of people back to the idea of what’s important to them,” she said.

While most pandemic restrictions have been lifted, some area parishes are holding Easter Sunday services outside, including a 6 a.m. sunrise Mass near the waterfront in South Boston.

Hundreds of people lit candles in the vast Cathedral of St. Paul, Minnesota, after Archbishop Bernard Hebda blessed the fire and lit the Paschal Candle to open the Easter Vigil service late Saturday.

The century-old cathedral echoed with the singing of the congregation as candles flickered in the darkness. Well past 8 p.m., wide-eyed children fascinated by the little flames and the cantors far outnumbered people wearing masks – the archdiocese rescinded all Covid protocols on April 1, while allowing the faithful and individual parishes to retain precautions if they wishes

10:14 a.m.: Australia’s two-year long ban on cruise ships expires on Sunday, another step toward the rehabilitation of tourism from the damage wrought by the pandemic.

The ban on foreign cruise ships — imposed in March 2020 after a COVID-19 outbreak aboard the Ruby Princess spilled into Sydney once the vessel docked — cost the Australian economy more than A$10 billion ($7.4 billion), the Cruise Lines International Association estimates.

Operators “are preparing for a carefully managed resumption of operations in a sector that previously supported more than 18,000 Australian jobs,” the association said in a statement ahead of the ban’s expiry.

Australia’s states will determine when vessels can enter now the federal ban has run out. Safety steps include vaccination requirements for crew and passengers over 12 years old, as well as mask and COVID-19-testing protocols.

P&O Cruises Australia’s Pacific Explorer will be among the first ships to dock in Sydney Harbour on Monday ahead of a return to service at the end of May.

Before COVID-19, 1.6 million cruise passengers visited Sydney in 2017 and 2018, according to official figures. The pandemic hit cruise ships particularly hard after high-profile outbreaks that led a variety of ports to block access.

Tourism industry bodies say there’s significant pent-up demand for cruises but it remains unclear if the fear of the disease will permanently affect the sector. Travel shares globally have yet to recover the ground lost due to the pandemic and have trailed global equities significantly since the start of 2020.

Australia has relaxed border restrictions this year, relying on high vaccination rates under a strategy of learning to live with the coronavirus.

8:20 a.m. COVID-19 patients can harbour the coronavirus in their feces for months after infection, researchers found, stoking concern that its persistence can aggravate the immune system and cause long COVID symptoms.

In the largest study tracking SARS-CoV-2 RNA in feces and COVID-19 symptoms, scientists at California’s Stanford University found that about half of infected patients shed traces of the virus in their waste in the week after infection and almost 4{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} patients still emit them seven months later. The researchers also linked coronavirus RNA in feces to gastric upsets, and concluded that SARS-CoV-2 likely directly infects the gastrointestinal tract, where it may hide out.

“It raises the question that ongoing infections in hidden parts of the body may be important for long COVID,” said Ami Bhatt, a senior author on the study published online last week in the journal Med, and an associate professor of medicine and genetics at Stanford. Lingering virus might directly invade cells and damage tissues or produce proteins that are provoking the immune system, she said in an interview.

No one knows yet what causes the constellation of post-COVID-19 symptoms, often termed long COVID, that afflict from 5{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} to 80{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of people after a SARS-CoV-2 infection. It’s possible at least four different biological mechanisms lead to distinct conditions or subtypes of long COVID, said Akiko Iwasaki, a professor of immunobiology and molecular, cellular, and developmental biology at Yale University.

“Long COVID is likely multiple different diseases,” Iwasaki said last week in an interview in her lab in New Haven, Connecticut. In one of these forms, persistent SARS-CoV-2 may trigger a damaging immune response that leads to ailments that could be quelled with drugs that target the virus, she said.

8:20 a.m. COVID-19 patients can harbor the coronavirus in their feces for months after infection, researchers found, stoking concern that its persistence can aggravate the immune system and cause long COVID symptoms.

In the largest study tracking SARS-CoV-2 RNA in feces and COVID-19 symptoms, scientists at California’s Stanford University found that about half of infected patients shed traces of the virus in their waste in the week after infection and almost 4 per cent patients still emit them seven months later. The researchers also linked coronavirus RNA in feces to gastric upsets, and concluded that SARS-CoV-2 likely directly infects the gastrointestinal tract, where it may hide out.

“It raises the question that ongoing infections in hidden parts of the body may be important for long COVID,” said Ami Bhatt, a senior author on the study published online last week in the journal Med, and an associate professor of medicine and genetics at Stanford. Lingering virus might directly invade cells and damage tissues or produce proteins that are provoking the immune system, she said in an interview.

No one knows yet what causes the constellation of post-COVID-19 symptoms, often termed long COVID, that afflict from 5 per cent to 80 per cent of people after a SARS-CoV-2 infection. It’s possible at least four different biological mechanisms lead to distinct conditions or subtypes of long COVID, said Akiko Iwasaki, a professor of immunobiology and molecular, cellular, and developmental biology at Yale University.

“Long COVID is likely multiple different diseases,” Iwasaki said last week in an interview in her lab in New Haven, Connecticut. In one of these forms, persistent SARS-CoV-2 may trigger a damaging immune response that leads to ailments that could be quelled with drugs that target the virus, she said.

“I have heard anecdotally of people recovering from long COVID after antivirals or monoclonals,” said Iwasaki, who wants to collaborate on clinical studies of potential therapies. “I’m really excited at the possibility of testing direct antivirals and monoclonal antibodies” against long COVID, she said.

Pfizer Inc.’s Paxlovid received emergency use authorization from the Food and Drug Administration in December, introducing the first COVID-19 treatment taken in pill form. Pfizer doesn’t have any long COVID studies underway, but is assessing their possibility, the drugmaker said in an email.

8:19 a.m. Several businesses and residents have filed suit in state court in Pennsylvania seeking to overturn Philadelphia’s renewed indoor mask mandate scheduled to be enforced beginning Monday in an effort to halt a surge in COVID-19 infections.

The lawsuit, filed in Commonwealth Court on Saturday, said Philadelphia lacks the authority to impose such a mandate.

Philadelphia earlier this week became the first major U.S. city to reinstate its indoor mask mandate after reporting a sharp increase in coronavirus infections, with the city’s top health official saying she wanted to forestall a potential new wave driven by an omicron subvariant.

Attorney Thomas W. King III, who was among those involved in last year’s successful challenge to the statewide mask mandate in schools, said the city’s emergency order went against recommendations of the federal Centers for Disease Control and Prevention and “imposed a renegade standard unfound anywhere else in the world.”

The suit accuses city health officials of having “usurped the power and authority” of state lawmakers, the state department of health and the state advisory health board.

8:18 a.m. Australia’s two-year long ban on cruise ships expires on Sunday, another step toward the rehabilitation of tourism from the damage wrought by the pandemic.

The ban on foreign cruise ships — imposed in March 2020 after a COVID outbreak aboard the Ruby Princess spilled into Sydney once the vessel docked — cost the Australian economy more than A$10 billion ($7.4 billion), the Cruise Lines International Association estimates.

Operators “are preparing for a carefully managed resumption of operations in a sector that previously supported more than 18,000 Australian jobs,” the association said in a statement ahead of the ban’s expiry.

Australia’s states will determine when vessels can enter now the federal ban has run out. Safety steps include vaccination requirements for crew and passengers over 12 years old, as well as mask and Covid-testing protocols.

P&O Cruises Australia’s Pacific Explorer will be among the first ships to dock in Sydney Harbour on Monday ahead of a return to service at the end of May.

Before COVID, 1.6 million cruise passengers visited Sydney in 2017 and 2018, according to official figures. The pandemic hit cruise ships particularly hard after high-profile outbreaks that led a variety of ports to block access.

Tourism industry bodies say there’s significant pent-up demand for cruises but it remains unclear if the fear of the disease will permanently affect the sector. Travel shares globally have yet to recover the ground lost due to the pandemic and have trailed global equities significantly since the start of 2020.

Australia has relaxed border restrictions this year, relying on high vaccination rates under a strategy of learning to live with the coronavirus.

8:15 a.m. The Shanghai government urged the city’s elderly residents to make sure they are fully vaccinated and to get booster shots once the city’s lockdown is lifted.

Only 62{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of residents aged 60 or older had received two shots of COVID-related vaccines as of April 15, Wu Jinglei, director of the Shanghai Heath Commission, said at a briefing Sunday. Of these, 38{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} have had booster jabs, Wu said.

The risks from the Omicron variant of coronavirus for unvaccinated elderly people are high, based on the monitoring of domestic and overseas cases, with patients displaying severe, critical and in some cases fatal symptoms, Wu said.

Older people with diseases such as diabetes and high blood pressure can get vaccinated as long as they are taking their routine medicines and their symptoms are stable, he said.

Shanghai has reported 16 COVID cases with severe symptoms in the latest outbreak, 15 of whom are aged 70 years or older and most of them are unvaccinated and have “serious” chronic diseases.

City officials recorded 24,820 local COVID-19 infections for Saturday, 21,582 of them asymptomatic. While the case count is still “fairly high,” the ratio of infections detected among potentially risky people has fallen, Wu said.

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What channel is 76ers vs. Raptors on today? Game 1 TV schedule, live streams, start time for 2022 NBA playoff game

What channel is 76ers vs. Raptors on today? Game 1 TV schedule, live streams, start time for 2022 NBA playoff game

There is certainly a little something of a rivalry brewing amongst the Raptors and 76ers, who will satisfy in the opening spherical of the 2022 NBA Playoffs.

The series gets underway on Saturday, April 16 when the fourth-seeded 76ers host the fifth-seeded Raptors.

2022 marks the 3rd time that the two franchises have gone head-to-head in the postseason and the first time since 2019, which quite a few may remember as an instant vintage.

Extra: Raptors vs. 76ers: Predictions, routine, Tv set channels for 1st Round in 2022 NBA Playoffs

This time all-around, issues will look a little bit unique. For starters, the collection begins in Philly, exactly where the Raptors posted a 2- report during the 2021-22 frequent period.

Game 1 is an opportunity for each individual workforce to make a assertion. 

When the Raptors look to steal property courtroom benefit, the Sixers will seem to present a reminder that with Joel Embiid and James Harden, their title aspirations in 2022 are pretty serious.

A lot more: By The Numbers: 76ers’ Joel Embiid captures historic NBA scoring title

Toronto will lean on the championship DNA of its star duo of Pascal Siakam and Fred VanVleet, while OG Anunoby and Gary Trent Jr. stage into their largest playoff roles to day.

Rookie Scottie Barnes has an prospect to transform in a playoff debut to try to remember, as the 20-year-aged has rarely seemed like a rookie this time.

Here is all you have to have to know ahead of Sport 1.

Far more: Check out the NBA playoffs on Sling Television set (U.S. only)

What channel is Raptors vs. 76ers on?

  • Television channel (United States): ESPN
  • Dwell streaming: Sling Tv | View ESPN 

Raptors vs. 76ers will be broadcast on ESPN. Viewers can stream Raptors vs. 76ers on View ESPN, the ESPN Application or on Sling Television.

Viewers in the U.S. can stream each individual NBA playoff game live on SLING Tv. With the SLING Orange Sports activities Excess package deal, get $10 off your to start with thirty day period now with entry to ESPN, ESPN2, ESPN3, TNT and NBATV.

NBA Playoff online games on ABC are simulcast on ESPN3, which is bundled with SLING Orange, accessible for $35 for every thirty day period including $25 the 1st month for new subscribers.

What time does Raptors vs. 76ers begin?

  • Date: Saturday, April 16
  • Time: 6 p.m. ET | 3 p.m. PT

Raptors vs. 76ers is scheduled to tip off shortly soon after 6 p.m. ET. The game will be performed at Philadelphia’s Wells Fargo Middle.

Raptors vs. 76ers collection plan, Television channels

Activity 1 of the very best of seven collection will acquire spot on Saturday, April 16. The teams will have a a single-day crack ahead of they’re back at it for Activity 2 in Philadelphia on Monday, April 18. 

The collection will shift to Toronto for Video games 3 and 4 beginning on Wednesday, April 20. If there is a Video game 7, it will be performed on Saturday, April 30 in Philadelphia.

(All periods Eastern)

Day Video game Area Time Television channel
April 16 Video game 1 Wells Fargo Heart 6 p.m. ESPN
April 18 Video game 2 Wells Fargo Middle 7:30 p.m. TNT
April 20 Activity 3 Scotiabank Arena 8 p.m. NBATV
April 23 Sport 4 Scotiabank Arena 2 p.m. TNT
April 25 Game 5* Wells Fargo Center TBD TBD
April 28 Game 6* Scotiabank Arena TBD TBD
April 30 Video game 7* Wells Fargo Center TBD TBD

*If essential

Coronavirus news and updates for Friday, April 15, 2022

Coronavirus news and updates for Friday, April 15, 2022

The latest coronavirus news from Canada and around the world Friday. This file will be updated throughout the day. Web links to longer stories if available.

8:54 p.m.: It’s gonna be an egg-stra special day on Monday when the White House Easter Egg Roll returns from a two-year hiatus due to the COVID-19 pandemic.

President Joe Biden and first lady Jill Biden are expected to welcome some 30,000 kids and their adult chaperones for the egg roll, an egg hunt and other activities.

The annual egg rolling event was canceled by former President Donald Trump in 2020 and by Biden last year due to the pandemic that has killed nearly 1 million Americans.

First Lady Jill Biden, an educator, has dubbed this year’s all-day event the “Egg-ucation Roll,” aides said, turning the South Lawn into a school community with various educational stations.

Besides eggs-treme fun, the all-day event will include a schoolhouse activity area, reading nook, talent show, obstacle course and other exercise stations, and a cafe where kids will learn to make and eat supposedly healthy treats.

The shindig also includes celebs like “Tonight Show” host Jimmy Fallon, singer Ciara and actor/singer Kristin Chenoweth.

More than two dozen costumed characters will roam the grounds, including Dr. Seuss’ The Cat in the Hat, the Racing Presidents mascots for the Washington Nationals of Major League Baseball, Rosita and Cookie Monster from “Sesame Street” and Snoopy and Charlie Brown, among others.

8 p.m.: After a sustained pandemic-induced dip in air travel, Canadians are slowly starting to board flights again. International arrivals are up compared to last year, Statistics Canada data shows, although still significantly below pre-pandemic levels.

While people are on the move, the country is staring down a sixth wave of COVID-19 infections — driven by the BA. 2 variant spreads and the lifting of public health measures.

System-wide decisions, from mask mandates to access to testing, have a significant impact on overall safety, said Dr. Angela Rasmussen, a virologist at the Vaccine and Infectious Disease Organization (VIDO) at the University of Saskatchewan. These policies also reduce the chance that Canadian travellers will take the virus elsewhere.

Yet travellers can still make the best of the tools at their disposal to keep themselves and others safe. Speaking to the Star, Rasmussen — who is about to attend a work conference in Portugal — shared her advice on how to navigate travel in the age of Omicron.

Click here to read more of this story from the Star’s Sara Mojtahedzadeh.

7:22 p.m.: The 75-year-old Republican said in an announcement late Friday he was diagnosed by his personal physician after experiencing mild symptoms such as a runny nose, head ache, body aches and a sore throat.

DeWine was administered a monoclonal antibody treatment, which is designed to fight the infection. He said he is following the U.S. Centers for Disease Control and Prevention protocol and quarantining.

The governor’s office said First Lady Fran DeWine was experiencing no symptoms and has tested negative. Both the governor and his wife have received two coronavirus vaccines and a booster.

DeWine’s diagnosis comes just 18 days before Ohio’s May 3 primary, in which he faces two Republican challengers, and just eight days before former President Donald Trump plans an Ohio rally.

It was unclear whether his diagnosis would affect DeWine’s attendance at the rally, or if he would have attended in any case. He had previous plans to attend a celebration of the 200th birthday of President Ulysses S. Grant, an Ohio native, on that day.

DeWine tested positive for COVID-19 once before, in 2020, before testing negative later the same day. Those conflicting results came just before the governor was to meet with Trump, then the president, in Cleveland.

4:55 p.m.: Yet again, the U.S. is trudging into what could be another COVID-19 surge, with cases rising nationally and in most states after a two-month decline.

One big unknown? “We don’t know how high that mountain’s gonna grow,” said Dr. Stuart Campbell Ray, an infectious disease expert at Johns Hopkins University.

No one expects a peak nearly as high as the last one, when the contagious omicron version of the coronavirus ripped through the population.

But experts warn that the coming wave – caused by a mutant called BA.2 that’s thought to be about 30 per cent more contagious – will wash across the nation. They worry that hospitalizations, which are already ticking up in some parts of the Northeast, will rise in a growing number of states in the coming weeks. And the case wave will be bigger than it looks, they say, because reported numbers are vast undercounts as more people test at home without reporting their infections or skip testing altogether.

2:02 p.m. A hospital in western Quebec is suspending its obstetrics services for the holiday weekend due to a lack of staff.

The health authority for the Abitibi-Témiscamingue region says the service at the hospital in Ville-Marie is suspended until Monday at 8 a.m. due to an unforeseen staffing issue.

The Centre intégré de santé et de services sociaux de l’Abitibi-Témiscamingue says on Facebook that it has reached out to women who are affected by the closure, and those giving birth will be redirected to another hospital about 130 kilometres away.

The health authority also announced on Thursday that emergency services at the Témiscaming-Kipawa health facility would be closed Friday, Saturday and Sunday night from 7:30 p.m. to 7:30 a.m.

Quebec’s health minister has warned that the province’s health services are looking at a difficult few weeks ahead as they struggle with a sixth wave of COVID-19 coupled with a rise in influenza and other viruses.

While officials did not say what caused the closures in Abitibi-Témiscamingue, the province has said about 13,000 health workers are off the job due to COVID-19.

1:08 p.m. Los Angeles County on Friday ended its order to quarantine asymptomatic people exposed to the coronavirus.

The rule change means anyone — even someone not vaccinated for COVID-19 or up-to-date with a booster shot — who is exposed to an infected person no longer needs to stay home for at least five days to see whether they will test positive or become sick, provided they remain symptom-free.

But unlike the California Department of Public Health, which universally relaxed its quarantine recommendations for the public earlier this month, L.A. County has established a few conditions for waiving the waiting period.

The county will require, not merely recommend, that people who were in close contact with an infected person “wear a highly protective mask around others, especially indoors, for a total of 10 days after the last contact with a person infected” with the coronavirus, and get tested within three to five days after their last exposure to the infected person.

Anyone who lives or works in L.A. County is subject to that masking order.

Someone is considered exposed to the coronavirus if they share the same indoor airspace — like a home, clinic waiting room or airplane — with an infected person during his or her contagious period for at least 15 minutes over a 24-hour period.

12:46 p.m. Yet again, the U.S. is trudging into what could be another COVID-19 surge, with cases rising nationally and in most states after a two-month decline.

One big unknown? “We don’t know how high that mountain’s gonna grow,” said Dr. Stuart Campbell Ray, an infectious disease expert at Johns Hopkins University.

No one expects a peak nearly as high as the last one, when the contagious omicron version of the coronavirus ripped through the population.

But experts warn that the coming wave – caused by a mutant called BA.2 that’s thought to be about 30 per cent more contagious – will wash across the nation and push up hospitalizations in a growing number of states in the coming weeks. And the case wave will be bigger than it looks, they say, because reported numbers are vast undercounts as more people test at home without reporting their infections or skip testing altogether.

At the height of the previous omicron surge, reported daily cases reached into the hundreds of thousands. On April 14, the seven-day rolling average for daily new cases rose to 39,521, up from 30,724 two weeks earlier, according to data from Johns Hopkins collected by The Associated Press.

11:41 a.m. Starting Monday, Minneapolis students will no longer have to wear masks at school or on buses, the school district said Thursday as it announced changes to its COVID-19 protocols.

The news came two days after St. Paul’s school board voted 6-1 to change the mask policy for that district, removing the mandate and allowing students and faculty to choose whether or not to wear a face covering in school buildings.

Besides dropping its mask mandate, Minneapolis Public Schools (MPS) will discontinue universal contract tracing, officials said. That means families may not be notified if someone in their student’s class tests positive for COVID-19.

District officials also said that beginning Monday, fully vaccinated students and staff will no longer be required to isolate after COVID-19 exposure and the quarantine time for unvaccinated students and adults in the schools will drop from 10 days to five days.

10:27 a.m. A Toronto public school board committee that advocates on behalf of students with special needs wants to bring back mandatory masking and vaccination for those who work with medically fragile children.

The Special Education Advisory Committee has written to the province’s top doctor requesting permission for the board to reintroduce masking rules and its vaccination policy at congregated schools that serve students with complex special needs, many of whom have multiple disabilities.

“Recent changes to COVID-19 safety measures, specifically regarding masking and vaccination requirements, have put these students at great risk of contracting the virus,” say SEAC members in a letter to the chief medical officer of health, Dr. Kieran Moore. “The COVID-19 virus poses great risks for any of these students, as it may exacerbate existing symptoms of their already complex disabilities and medical fragilities.”

Read the full story from the Star’s Isabel Teotonio

5:58 a.m.: Small business owners have made a plea to the federal finance minister to consider more help paying off their pandemic-related debts as the sixth wave of COVID-19 causes customers to stay home and sales to fall.

The request is one Finance Minister Chrystia Freeland has faced repeatedly in recent days during a cross-country post-budget tour.

Her response has been that emergency measures are no longer needed with the crisis passed, the economy running hot and the government needing to tighten its fiscal belt.

Dan Kelly, president of the Canadian Federation of Independent Business, said underneath the headline economic numbers only two in five of his members report being back to normal sales.

He said more are worried about the impact on revenues and their ability to repay loans with people staying home despite provinces removing public health restrictions.

His members put those concerns to Freeland during a webinar on the budget and Kelly said he walked away believing the finance minister heard their concerns.

The budget doesn’t include any further extensions of emergency benefit programs that will come to a close on May 7, but Freeland told those on the webinar, “I hear you,” when asked about debt relief, adding a moment later, “let’s keep on talking.”

Thursday, 9:35 p.m.: California is sticking with its coronavirus vaccine mandate for schoolchildren, but it won’t happen until at least the summer of 2023, Gov. Gavin Newsom’s administration announced Thursday.

Last year, California was the first state to announce it would require all schoolchildren to receive the coronavirus vaccine. But it hasn’t happened yet because Newsom said he was waiting for regulators at the U.S. Food and Drug Administration to give final approval to the vaccine for school-aged children.

At the time, Newsom estimated the mandate would take effect for the start of the 2022-23 school year. But while federal regulators have authorized use of the coronavirus vaccine for children as young as 5 in an emergency, it has still not given final approval to anyone younger than 16.

As the calendar inches closer to the fall, school administrators had worried they would not have enough time to implement the vaccine mandate.

“So based on these two facts — we don’t have full FDA approval, and we recognize the implementation challenges that schools and school leaders would face — that we are not moving to have a vaccine requirement for schools in this coming academic year and no sooner than July 2023,” California Health and Human Services Secretary Dr. Mark Ghaly said in an interview.

Read Thursday’s coronavirus news.

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Elon Musk offers to buy Twitter for $43 billion, so it can be ‘transformed as private company’

Elon Musk offers to buy Twitter for $43 billion, so it can be ‘transformed as private company’

Elon Musk provided to purchase Twitter for $54.20 a share in a submitting printed Thursday, declaring the social media firm needs to be reworked privately, a little about a 7 days after revealing a 9.1{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} stake in the business. Musk’s offer you values Twitter at about $43 billion.

“I invested in Twitter as I believe in its opportunity to be the platform for free speech around the world, and I believe that no cost speech is a societal imperative for a operating democracy,” Musk wrote in a letter despatched to Twitter Chairman Bret Taylor and disclosed in a securities filing.

Twitter shares shut down 1.68{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} on Thursday. Tesla’s stock dipped extra than 3.6{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} on the information.

According to Musk, the social media business requirements to go personal because it can “neither thrive nor provide” free of charge speech in its existing state.

“As a outcome, I am featuring to purchase 100{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of Twitter for $54.20 for every share in hard cash, a 54{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} quality in excess of the working day just before I began investing in Twitter and a 38{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} premium in excess of the day ahead of my investment decision was publicly declared,” he wrote. “My offer you is my greatest and remaining supply and if it is not approved, I would need to have to reconsider my placement as a shareholder.”

Musk tapped Morgan Stanley as a fiscal advisor, in accordance to the submitting.

He claimed later on on Thursday during a converse at TED2022 that he is not intrigued in buying Twitter to make cash off it and even mentioned he is not certain if he’ll even be able to buy the corporation.

Inventory picks and investing trends from CNBC Pro:

“This is not a way to form of make income… it truly is just that I imagine my potent, intuitive sense is that acquiring a public platform that is maximally reliable and broadly inclusive, is very significant to the foreseeable future of civilization,” Musk said at TED2022. “But yeah, I do not care about the economics at all.”

He also mentioned during the speak that he would try to keep as lots of shareholders as attainable for a non-public organization.

The information will come just times right after Twitter CEO Parag Agrawal warned investors of “interruptions in advance.”

“The Twitter Board of Administrators will thoroughly overview the proposal to decide the class of action that it believes is in the greatest fascination of the Firm and all Twitter stockholders,” the enterprise claimed in a assertion Thursday in response to the offer you. CNBC’s David Faber documented on “Squawk on the Road” that Twitter’s board will meet up with at 10 a.m. to examine the bid, for each individuals common.

Musk first disclosed his stake in the social media big on April 4. He later on landed a seat on the company’s board of directors just before reversing those programs.

The Tesla CEO has earlier criticized the social media big publicly, polling people today on Twitter very last month about no matter whether the organization abides by totally free speech principles. He also said he was taking into consideration setting up a new social media platform.

Shares of Twitter have seesawed in modern months amid the information from Musk, but are up 6{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} this yr and 18.5{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} due to the fact the get started of the thirty day period.

Here is the letter Musk despatched as disclosed in a securities filing:

I invested in Twitter as I consider in its opportunity to be the system for totally free speech all-around the globe, and I imagine cost-free speech is a societal vital for a operating democracy.

Having said that, considering that building my investment decision I now understand the enterprise will neither thrive nor provide this societal critical in its current type. Twitter needs to be transformed as a private organization.

As a result, I am presenting to obtain 100{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of Twitter for $54.20 for each share in money, a 54{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} premium in excess of the working day before I started investing in Twitter and a 38{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} high quality around the day prior to my investment decision was publicly introduced. My present is my most effective and ultimate present and if it is not acknowledged, I would need to rethink my place as a shareholder.

Twitter has extraordinary possible. I will unlock it.

Elon Musk

Later on Thursday, Agrawal reportedly instructed staff members in a personnel assembly that the firm is assessing the present.

Baker Mayfield on Cleveland Browns: ‘I feel disrespected 100{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809}’

Baker Mayfield on Cleveland Browns: ‘I feel disrespected 100{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809}’

Common corticosteroid drug may aid weight loss

Common corticosteroid drug may aid weight loss

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New exploration in mice implies prednisone, a widespread corticosteroid drug, may possibly assist body weight reduction. Sean Locke/Stocksy
  • Many men and women with conditions that include serious inflammation choose a everyday dose of a corticosteroid drug identified as prednisone.
  • The drug is extremely helpful but can induce weight get, muscle mass squandering, and other significant side effects.
  • A new analyze in mice has observed that a weekly dose of the exact drug could have the reverse influence, creating muscle toughness and endorsing fat decline.
  • A great deal study stays to be completed, but the scientists speculate that weekly prednisone could reduce aspect effects and reduce or take care of obesity.

Prednisone is a corticosteroid drug that decreases inflammation in a vast array of situations, like muscular dystrophy, bronchial asthma, colitis, arthritis, and psoriasis.

Having said that, whilst the treatment is really powerful, day by day prednisone can induce bodyweight attain and muscle losing, amid other serious side consequences.

Scientists are keen to find out regardless of whether a weekly dose of prednisone could give the identical anti-inflammatory benefits as a day-to-day dose, but with out advertising and marketing body weight acquire and losing.

In a not too long ago printed pilot analyze, scientists at Northwestern University Feinberg School of Medicine in Chicago, IL, identified that a as soon as-weekly dose of prednisone enhanced muscle mass efficiency in people with muscular dystrophy.

Compared with a everyday dose, the weekly procedure did not appear to bring about the common facet outcomes of corticosteroid treatment method, these types of as weight achieve, large blood sugar, and superior blood pressure.

There had been also no really serious adverse events or persistent facet results from the cure.

Regardless of whether the identical method could avert pounds attain and muscle mass losing in people who do not have muscular dystrophy is unclear, however.

To start out to solution that query, a person of the researchers has now in contrast each day and weekly prednisone in mice fed a large fat diet plan. Elizabeth M. McNallly, Professor of Medication (Cardiology) and Biochemistry and Molecular Genetics from Northwestern College Feinberg Faculty of Medication in Chicago, IL, led the review.

They located that a weekly dose prevented obesity and improved muscle mass metabolism in the animals.

By contrast, a daily dose of the drug led to pounds attain, exercising intolerance, and large blood sugar concentrations.

In addition, mice that were being presently overweight missing excess weight, obtained energy and improved their lean system mass on a weekly dose of prednisone — despite eating a high-fats diet regime.

The study has been revealed in the Journal of Experimental Medication.

“What is fascinating to me about this work is the acquiring that a straightforward improve in the dosing frequency can rework [corticosteroid drugs] from inducers to preventers of being overweight.”

Mattia Quattrocelli, Ph.D., corresponding creator

Dr. Quattrocelli, who initiated the research even though at Northwestern, is now assistant professor at Cincinnati Children’s Healthcare facility Health-related Center and the pediatrics section at the College of Cincinnati.

The study adds to proof that a healthful, well balanced metabolism largely is dependent on the molecular “conversation” in between unwanted fat (adipose) tissue and muscles.

The researchers uncovered that in obese mice, a the moment-weekly dose of prednisone greater the volume of a signaling molecule that adipose tissue produces.

The molecule — a hormone referred to as adiponectin that is derived from fats — improved the physical exercise tolerance and energy expenditure of the animals’ muscles.

Conversely, mice that had been genetically engineered to absence adiponectin failed to respond to the once-weekly cure with prednisone.

Dr. Quattrocelli advised Medical Information Currently that researchers will will need to discover more about the mechanisms guiding the discovery before they can translate the conclusions into therapies.

“We very first have to have to collect more mechanisms in mice and potentially other animal styles in get to figure out the degree of translatability,” he explained.

“There’s really a little bit of distinction amongst obesity in mice and being overweight in human beings, and in common involving metabolic pressure in mice and metabolic anxiety in people,” he emphasized.

He additional that muscle mass in mice has a different composition to that in people, with a bigger proportion of “fast twitch” fibers.

“On top of that I want to deliver to the fore the worth of the complexity of social behavior in human beings in comparison to mice,” he mentioned.

“As human beings we have extremely, quite advanced social behaviors that directly affect when and how we try to eat and the dynamics of overall body mass in standard,” he additional.

By distinction, researchers can tightly regulate the availability of food items and other environmental things in the cages of lab mice.

“This examine provides up a really exclusive and interesting concept that has yet to be explored further more,” claimed Dr. Revital Gorodeski Baskin, an endocrinology and diabetic issues professional, and director of obesity at University Hospitals in Cleveland, OH.

“I am enthusiastic to see that just after just one significant dose of prednisone, these mice showed enhancement in physique mass, muscle mass fat burning capacity, and electrical power expenditure,” she instructed MNT.

“This might seem like a feasible treatment method tactic for obesity, with a few concerns,” Dr. Baskin additional.

She pointed out that a solitary, large dose of a steroid can result in psychological distress, poor snooze, paranoid thoughts, and stress in some men and women.

She explained substantial doses of steroids are regarded to minimize bone density and increase an infection rates, so scientists would need to examine no matter if shorter bursts of the prescription drugs could, around time, result in the similar concerns.

The scientific gains could also wane in excess of time as patients’ bodies accommodate to the therapy.

“I do, nevertheless, think that this is a very distinctive thought to advancement in energy metabolism and entire body mass,” Dr. Baskin additional. She said she looked ahead to observing further analysis into the idea.