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Nutson’s Weekly Auto News Wrap-up: January 16-22, 2022


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Auto CENTRAL CHICAGO – January 23, 2022 Each and every Sunday Larry Nutson, The Chicago Car or truck Guy and Govt Producer, with capable help from senior editor Thom Cannell from The Vehicle Channel Michigan Bureau, compile The Automobile Channel’s “acquire” on this previous week’s automotive information, condensed into straightforward to digest news Nuggets.

Master Far more: Entire variations of present-day information nuggets together with 1000’s of web pages of suitable information and viewpoints, info stored in a million web page library printed and indexed on The Auto Channel all through the earlier 25 yrs. Finish information can be discovered by copying a daring headline and then inserting into any Internet site Search Box.

Nutson’s Automotive News Wrap-up – Week Ending January 22, 2022 Below are the earlier week’s significant, suitable, semi-mystery, or snappy automotive news, opinions and insider back stories presented as
expertly crafted simple-to-fully grasp automotive universe information nuggets.

* From Our Pal Paul A. Eisenstein, Publisher Of theDetroitBureau.com

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Marty Bernstein, The Car Channel’s Senior Editor-at-substantial handed away this week at age 89.
Marty was a sharp dresser, with a sharp wit and an incisive ability to reduce by all the nonsense normally heaped on a journalist.

It might be uncomplicated to tumble into cliché and call Marty Bernstein the “dean of auto writers.” After all, he was far more than 2 times — certainly, triple — the age of many who acquire aspect in the touring circus of vehicle exhibits, new car previews, driving reviews and peer to peer interviews with executives who make the around the globe car industry go, they all talked with Marty. But he was much additional than that. He could be a mentor, if that was what the minute termed for. A source of insight. A fount of wonderful stories. And, until eventually incredibly late in lifetime, a major challenger on the tennis court.

The very last 12 months have been significantly rough. But, he by no means misplaced his keen eye and, even on the worst of times, he’d roll out a joke in his rumbling voice. Marty Bernstein passed this week with the similar amount of dignity that described the rest of his long existence.

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Marty Bernstein was laid to relaxation on Jan. 21, 2022. He leaves behind his wife, Marti son Michael and daughter-in-regulation Jennifer Bernstein. The loved ones indicates donations be designed to the Kidney Basis, to Mazon, a Jewish firm dedicated to avoiding starvation, to the Chabad Center of Troy, or to a charity of your picking. They plan a celebration of his daily life sometime through the spring.

“May Marty’s memory be for a blessing”, Rest In Peace my pal and thank you for normally staying there for us…you will be skipped.

* DoE simple fact of the week. In product yr 2021 all-electrical automobiles had a median driving array about 60{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} that of gasoline powered vehicles. For the 2021 model yr, the median driving assortment of all-electrical cars (EV) was 234 miles when the median vary for gasoline automobiles was 403 miles. Whilst this is a sizeable distinction, EV ranges have been escalating swiftly. When the greatest selection for any EV made available in the 2021 design year was 405 miles, there are now EV versions supplied for the 2022 model calendar year reaching a greatest assortment of much more than 500 miles. As a lot more lengthy vary EVs develop into available, the discrepancy in assortment concerning gasoline powered automobiles and EVs is likely to keep on to slim.

* In June 2022, BMW will make the really last V12 motor at any time to be fitted to a BMW collection output highway vehicle. To mark the celebration, BMW will offer you The Remaining V12 a confined series of 12 cars for consumers in the US. Primarily based on the BMW M760i xDrive, these will be 12 of the previous V12 BMW automobiles crafted for the US current market and will be distinguished by exclusive badging, wheels, and a decision from the extensive assortment of exterior colours and upholstery offered by BMW Particular person. BMW launched their to start with roadgoing V12 in 1987.

* Reuters studies that Germany is hedging on BEVs. A major official of the new German governing administration has walked back again the country’s target of owning 15 million EVs on the road by 2030. The pledge now involves hybrids AND EVs. Germany now has 1 million electrified autos on the road, 50 {cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of which are hybrids. Obtaining to 15 million by 2030 will be a stretch both way the government counts.

* And a single additional from Reuters: Oil large BP stated its EV recharging stations could shortly be as successful as gasoline pumps. If BP and its rivals start off accelerating the speed of EV charger set up, you can expect to know the tipping place has certainly arrived.

* From AP we read through, California prosecutors have submitted two counts of vehicular manslaughter from the driver of a Tesla on Autopilot who ran a red light-weight, slammed into one more car and killed two individuals in 2019. The defendant appears to be the very first human being to be charged with a felony in the United States for a deadly crash involving a motorist who was utilizing a partially automated driving system. Los Angeles County prosecutors submitted the rates in Oct, but they came to mild only last 7 days. The misuse of Autopilot, which can command steering, speed and braking, has occurred on several situations and is the matter of investigations by two federal agencies.

* The Insurance policy Institute for Freeway Safety (IIHS) is producing a new rankings system that evaluates the safeguards that motor vehicles with partial automation employ to enable drivers continue to be targeted on the highway. The new score system is for motor vehicles with partial automation but no automobile on the current market can move with out changes. Irrespective of misleading messaging from some companies, for now, at the very least, self-driving cars and trucks are not accessible to people. IIHS expects to difficulty the to start with set of rankings in 2022.

* Reuters stories the French govt desires automakers to include things like cigarette fashion health and fitness warnings as section of their ads, and vehicle corporations are not content, the Economical Instances reviews. A French authorities rule would require disclaimers in car adverts such as “for limited journeys stroll or acquire a bike, when possible,” or “take into account auto pooling.”

* Ford is recalling about 200,000 vehicles in the U.S. to resolve a trouble that can halt the brake lights from turning off. The remember handles certain 2014 and 2015 Ford Fusion and Lincoln MKZ midsize vehicles as very well as some 2015 Mustangs. All have been marketed or registered in Texas, Louisiana, Mississippi, Alabama, Florida, Ga, South Carolina, North Carolina, Virginia and Hawaii.

* The Washington, D.C. Auto Present opened its doorways this week to representatives of the automotive industry, federal government officials, and associates of the media all through its official General public Policy Working day. Regarded on the automobile circuit as the formal “Community Coverage Clearly show”, the day resolved the innovations and troubles for the country’s crucial automotive sector. It is really a exhibit for the people in federal agencies and in Congress, and not so substantially about new vehicles and vehicles.

* The Chevrolet Corvette celebrated its 69th birthday this week. The Corvette designed its debut on Jan. 17, 1953 at the Waldorf-Astoria in New York Town.

* The legendary Hirohata Mercury marketed for $1.95 million very last 7 days at the Mecum collector auto auction in Kissimmee, Fla. This famed “leadsled” tailor made 1951 Mercury is a primary instance of the custom made auto scene that blossomed in midcentury Southern California. The overall body was developed by George Barris, the interior by Carson Leading Shop and pinstriping was carried out by Kenneth Howard, far better known as the artist Von Dutch.

*Dodge is in look for of an influencer for its model. It really is not a whole-time occupation, but anybody can apply for the position with perks like $150,000, a corporation SRT Hellcat for a calendar year, the capacity to fulfill with Dodge engineers about what’s to arrive from the manufacturer, Dodge goods and receiving to show up at activities from the racing keep track of to the North American International Vehicle Present in Detroit. The ambassador will share his or her ordeals on the web. Applicants will have to submit a maximum two-minute video displaying why they really should be the chief donut maker. Applications are thanks by Feb. 28. The 1st 10,000 will be reviewed. Followers can utilize or abide by alongside at DodgeGarage.com. https://www.dodgegarage.com

* Dale Earnhardt Jr. joined his dad in the NASCAR Hall of Fame. Earnhardt alongside with late-design driver Pink Farmer and the late Mike Stefanik, a embellished modified driver who died in a plane crash in 2019, were being inducted this week in the 2021 course. It is NASCAR’s 12th Hall of Fame class and the to start with with just 3 new inductees. For the past 11 many years the HoF experienced a five member course but transformed the procedures setting up in 2021. Ralph Seagraves was named as the recipient of the Landmark Award for Exceptional Contributions to NASCAR.

Remain secure. Be Well.

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Apple cider vinegar shots: Benefits, risks, and recipe

Apple cider vinegar (ACV) shots are tiny drinks that contain a combination of ACV with another liquid. Some shots also consist of other substances, this sort of as spices or sweeteners.

Some exploration implies that ACV has wellbeing gains, these as advertising balanced cholesterol and blood glucose stages. Nevertheless, consuming concentrated ACV can erode tooth enamel and irritate the esophagus, or foods pipe.

To avoid facet outcomes, persons must restrict their consumption of ACV to 15 milliliters (ml) for each working day — equivalent to 1 tablespoon — and dilute it in a tall glass of h2o.

Retain reading to master far more about the added benefits and challenges of ACV pictures, as well as how to acquire them securely and make them at home.

ACV pictures are small beverages that comprise ACV, normally with a tiny total of yet another liquid, these kinds of as a fruit juice or drinking water.

It is attainable to make ACV photographs at house or invest in ready-produced kinds in retailers. Commercially out there ACV shots occasionally comprise other components, which may well contain:

ACV is apple juice that has been through fermentation 2 times. The very first fermentation will involve mixing apple juice with yeast and a carbohydrate. This alterations the carbs into alcoholic beverages. The 2nd fermentation turns the alcoholic beverages into acetic acid, which provides ACV its acidity.

Even though there is some investigation about the probable health and fitness gains of ACV in typical, there is no exploration on the rewards of using ACV as a shot. It is most likely that it is no more useful than consuming ACV in other methods, this kind of as in a glass of water or as an component in meals, such as salad dressings.

For folks who do not like the flavor of ACV, it may be easier to drink as a shot.

ACV, additional normally, may have some practical wellness gains. Study suggests it may:

Enhance cholesterol and glucose degrees

Substantial cholesterol and blood glucose are possibility components for many cardiovascular disorders. These ailments are a leading trigger of untimely loss of life.

A 2021 review evaluated 9 scientific tests on the outcomes of ACV and found that the vinegar may perhaps encourage much healthier blood lipid and glucose degrees. This may possibly aid people today decrease the hazard of cardiovascular problems in mixture with other interventions, these as a balanced diet program.

Nevertheless, the review notes that because of to some limitations, people today need to interpret these conclusions with caution and that more investigate is needed to validate the consequences. ACV is not a alternative for medical treatment method.

Increase immunity

Bacterial strains are more and more getting to be resistant to antibiotics, so experts are seeking for alternatives to improve immunity and combat bacterial bacterial infections. With this intent, exploration in 2018 examined preliminary animal and test-tube scientific studies on the antimicrobial effects of ACV.

It concluded that the vinegar has antimicrobial consequences in opposition to Escherichia coli, Staphylococcus aureus, and Candida albicans, as well as lessening swelling through an infection. Far more investigate is required to recognize if ACV can support decrease these microbes in humans.

Advertise fat loss

A person more mature analyze implies that ACV could assist market weight reduction. The small scientific demo from 2009 compared the effects of consuming 15 and 30 ml of the vinegar for each working day with using a placebo.

Evaluation of the success indicated that daily consumption of ACV may perhaps lessen weight, human body mass index, stomach fat, and waistline circumference. Significantly more study is essential to verify that ACV impacts body body weight in a larger sized population.

A 2020 assessment assessed the aspect outcomes of ACV intake and concluded that it is probable harmless to get it in just recommended limitations. A 2021 paper states that the best ingestion is 15 ml per day (1 tbsp), which is the sum in numerous, but not all, shot recipes.

Nonetheless, consuming ACV as a shot carries many health and fitness dangers mainly because of the superior concentration of vinegar they comprise. Small amounts of ACV with satisfactory dilution is needed to keep away from the following:

Erosion of tooth enamel

Investigate in 2020 assessed the consequences of two times-every day use of 2 tbsp of apple cider vinegar mixed with 1 cup of drinking water. At the conclusion of the 8-7 days experiment, the scientists observed that the consume can erode tooth enamel.

Tooth enamel erosion is permanent and irreversible, so it is essential to keep away from procedures that could result in it where ever doable.

Hurt to esophagus

A 2019 scenario analyze documented a scenario of a teenager ingesting an undiluted fermented vinegar drink each individual working day for 1 thirty day period. This consume was strongly acidic, main to acid burns in the esophagus.

Although this is an isolated scenario, the authors of the analyze emphasize that undiluted vinegar beverages are corrosive. Ingesting them also frequently may possibly destruction the gastrointestinal tract.

Growth of osteoporosis

Some proof indicates that extreme ACV usage can add to weak or brittle bones.

For example, an older 1998 scenario examine claimed that a woman who drank 250 ml of ACV for every working day missing bone mineral density to the extent of developing osteoporosis.

When this is an serious situation, it is most effective for persons to drink no more ACV than medical practitioners advocate to prevent the risk of complications.

While members in the 2021 assessment consumed involving 15–770 ml of ACV per day, the researchers decided that 15 ml for every working day is the optimum dose. This is equal to 1 tbsp.

For small chance, persons ought to dilute 1 tbsp of ACV in a tall glass of water. Diluting in fruit juice is not as helpful due to the fact fruit juice is also acidic.

For supplemental security of the tooth, individuals can consume the ACV water by means of a straw. Rinse the mouth with plain drinking water afterward.

Beneath are two ACV shot recipes individuals may well desire to consider. To secure the enamel, it is highly recommended to comply with the instructions higher than for consuming ACV safely and securely.

Apple and ginger

Components:

  • 1 tbsp ACV
  • ¼ cup unsweetened fruit juice
  • a pinch of freshly grated ginger

Blend the substances with each other in a bowl or blender until eventually incorporated.

Honey and spices

Substances:

  • 4 tbsp warm drinking water
  • 1 tbsp honey or maple syrup
  • 1 tbsp ACV
  • pinch ground cinnamon or turmeric

Add the heat h2o and honey or maple syrup to a Mason jar and shake until it dissolves. Then increase the other ingredients and stir.

ACV photographs consist of vinegar blended with a different liquid, these as h2o or fruit juice. They are little in measurement and may possibly have other components, this sort of as spices or sweeteners.

Some exploration signifies that ACV has some well being advantages. It may possibly enable to cut down substantial cholesterol and control blood glucose levels. Nevertheless, there is no unique profit to getting ACV as a shot. Executing so may possibly hurt the teeth or throat because of to the acidity of the combination.

People today who want to consider ACV for its overall health added benefits can reduce the prospect of side results by mixing no additional than 1 tbsp of ACV in a tall glass of water. They may perhaps also wish to drink it via a straw.

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Bills vs. Chiefs final score, results: KC wins OT thriller, reaches fourth consecutive AFC championship

The Chiefs are headed to the 2022 AFC championship game after a thrilling 42-36 overtime win over the Bills in the divisional round Sunday night in Kansas City, Mo. 

All four divisional games this weekend were determined on the final play of the game, but the Chiefs were the only home team to win and the only team to win with a touchdown rather than a field goal. 

The last four drives of regulation produced 25 total points in final two minutes: Bills touchdown and 2-point conversion, Chiefs touchdown, Bills touchdown, Chiefs field goal. The Bills took a three-point lead with 13 seconds remaining, but the Chiefs quickly got into field goal range as Patrick Mahomes connected with Tyreek Hill for a 19-yard completion and Travis Kelce for a 25-yard pass play. Harrison Butker’s 49-yard field goal sent the game into overtime. This was redemption for Butker, who missed a 50-yard field goal attempt and an extra point kick earlier in the game.

Mahomes’ and Josh Allen’s stat lines Sunday were extremely similar. Mahomes finished with 378 yards and three touchdowns passing, while Allen finished with 329 yards and four touchdowns. Mahomes rushed for 69 yards and one touchdown, while Allen had 68 rushing yards. 

Bills wide receiver Gabriel Davis set an NFL single-game playoff record with four receiving touchdowns. He scored all four of the Bills’ touchdowns and finished with 201 receiving yards.

The Chiefs will host the Bengals next Sunday afternoon in the AFC championship game. This will be Kansas City’s fourth consecutive AFC championship appearance.

Sporting News tracked live scoring updates and highlights from Bills vs. Chiefs on Sunday. Read below for complete results from the 2022 NFL divisional playoff game.

MORE: Watch NFL games live with fuboTV (free trial)

Bills vs. Chiefs score

  Q1 Q2 Q3 Q4 F
Bills 7 7 7 15 36
Chiefs 7 7 9 13 42

Bills vs. Chiefs live updates, highlights from NFL playoffs

(All times Eastern.)

End of game: Chiefs 42, Bills 36

9:55 p.m. — TOUCHDOWN, CHIEFS. Kelce catches an eight-yard pass for touchdown and for the win. Chiefs 42, Bills 36.

9:54 p.m. — Hardman rushes 26 yards to the Bills’ 8-yard line. The Chiefs are now set up for 1st-&-Goal.

9:53 p.m. — The Chiefs make it into Bills territory after Hardman advances 16 yards. The Chiefs need a touchdown to win the game.

9:51 p.m. — The Chiefs won the coin toss and get the ball first. Kelce gives the Chiefs a first down, putting them on their own 44-yard line.

End of regulation: Chiefs 36, Bills 36

9:45 p.m. — FIELD GOAL, CHIEFS. Butker makes a 49-yard field goal to tie up the game as regulation ends. The game is headed to overtime. Chiefs 36, Bills 36.

9:44 p.m. — Kelce advances 25 yards to put the Chiefs in field goal range.

9:42 p.m. — Hill advances 19 yards to put the Chiefs closer to field goal range. They are on their own 44-yard line with eight seconds remaining.

9:39 p.m. — TOUCHDOWN, BILLS. Davis scores his fourth touchdown, this time with a 19-yard catch. Davis becomes the first player in playoff history to have four touchdown receptions. The Chiefs will get the ball with 13 seconds left. Bills 36, Chiefs 33.

9:38 p.m. — Emmanuel Sanders catches a 16-yard pass to put the Bills on the 19-yard line with 17 seconds left.

9:35 p.m. — Allen throws a long pass to Davis, who then advances for a total of 28 yards. The Bills are on the Chiefs’ 47-yard line with 49 seconds to go.

9:32 p.m. — TOUCHDOWN, CHIEFS. Hill scores a 64-yard touchdown to put the Chiefs back on top with a minute left of the game. Chiefs 33, Bills 29.

9:31 p.m. — Kelce catches an 11-yard pass for a Chiefs first down.

9:26 p.m. — TOUCHDOWN, BILLS. Davis was wide open to catch a 27-yard touchdown pass from Allen. The two-point conversion is good, caught by Stefon Diggs. Bills 29, Chiefs 26.

9:22 p.m. — Singletary is brought down for a loss of seven yards. The Bills are now on the 27-yard line on 4th-&-13 with two minutes left of the game.

9:19 p.m. — The Bills convert on fourth down after Allen runs six yards. The Chiefs defenders couldn’t stop him. The Bills are on the Chiefs’ 24-yard line.

9:12 p.m. — Allen runs nine yards to keep the Bills’ drive alive with 5:23 left of the game. He now has 53 rushing yards. The Bills are on the Chiefs’ 48-yard line.

9:05 p.m. — FIELD GOAL, CHIEFS. The Chiefs go three-and-out despite starting close to the end zone. Butker makes the 38-yard field goal. Chiefs 26, Bills 21.

9:01 p.m. — On the punt return, Hill runs 45 yards to the Bills’ 16 yard line. Hill was ultimately taken down by the punter, Matt Haack.

8:58 p.m. — Allen is sacked by Jarren Reed on third down for a loss of five yards. The Bills punt the ball.

8:55 p.m. — Davis catches a 17-yard pass from Allen to open up their drive.

8:52 p.m. — The Chiefs punt the ball after not reaching field goal range.

End of third quarter: Chiefs 23, Bills 21

8:45 p.m. — Mahomes rushes six yards. This is his first running play after he broke his single-game record for rushing yards with 63. He now has 69 after this play.

8:40 p.m. — TOUCHDOWN, BILLS. On the first play of the Bills drive, Allen throws a long pass to Davis for a 75-yard touchdown. It took the Bills 10 seconds to score this touchdown. Chiefs 23, Bills 21. 

8:36 p.m. — TOUCHDOWN, CHIEFS. Mecole Hardman runs 25 yards for a touchdown. The extra point is no good, though. Chiefs 23, Bills 14.

8:35 p.m. — Edwards-Helaire runs 20 yards to put the Chiefs on the Bills’ 25-yard line.

8:29 p.m. — On 4th-&-1, the Bills decide to punt instead of going for the conversion. It’s their third punt of the night.

8:23 p.m. — FIELD GOAL, CHIEFS. Butker just barely makes a 39-yard field goal to put the Chiefs on top. Chiefs 17, Bills 14.

8:19 p.m. — McKinnon advances 20 yards to the Bills’ 20-yard line. He leads the Chiefs for most total yards so far with 57.

8:16 p.m. — McKinnon gets the first first down of the half after rushing three yards on third down. 

End of second quarter: Bills 14, Chiefs 14

8:00 p.m. — Harrison Butker misses a 50-yard field goal attempt as time expires. 

7:56 p.m. — Kelce catches an eight-yard pass to put the Chiefs in field goal range on the Bills’ 32-yard line. 

7:54 p.m. — Hill advances 26 yards to put the Chiefs on the Bills’ 44-yard line. The Chiefs are about six yards short of field goal range.

7:50 p.m. — TOUCHDOWN, BILLS. Gabriel Davis catches an 18-yard pass from Allen and pushes into the end zone. The game is tied with 37 seconds left of the half. Bills 14, Chiefs 14.

7:46 p.m. — Cole Beasley completes the longest Bills play of the game for 24 yards. The Bills are on their own 49-yard line with a minute and a half left of the half.

7:42 p.m. — TOUCHDOWN, CHIEFS. Bryon Pringle catches a two-yard pass from Mahomes for the touchdown, giving the Chiefs their first lead of the game. Chiefs 14, Bills 7.

7:36 p.m. — Mahomes is sacked by Ed Oliver for a loss of seven yards. The Chiefs are still in spot for 2nd-&-Goal.

7:32 p.m. — Clyde Edwards-Helaire is back and gets the Chiefs their fourth consecutive first down. He ran 22 yards to the Bills’ 21-yard line.

7:31 p.m. — Mahomes throws a big first down pass to Travis Kelce for 21 yards. 

7:28 p.m. — The Bills also go three-and-out.

7:20 p.m. — The Chiefs go three-and-out.

7:15 p.m. — The BIlls punt for the first time all post season after Allen was sacked. Last week, the Bills went the entire game without punting.

7:12 p.m. — Allen adds to his rushing yards total after running 14 yards for a first down.

End of first quarter: Chiefs 7, Bills 7

7:08 p.m. — On third down, Stefon Diggs catches a five-yard pass to keep the Bills’ drive alive. 

7:01 p.m. — TOUCHDOWN, CHIEFS. Mahomes has a spectacular first drive, finishing it off with a touchdown. He ran eight yards for the touchdown. He finished the drive with 49 rushing yards, which is his most in a single drive in his career.  Chiefs 7, Bills 7.

6:59 p.m. — Mahomes runs for another first down, this time for seven yards. The Chiefs are on the Bills’ 13-yard line.

6:57 p.m. — Mahomes runs 34 yards for a huge first down. This is the biggest play of the game so far.

6:56 p.m. — Jerick McKinnon helps the Chiefs get their first first down after Patrick Mahomes escaped being sacked. 

6:49 p.m. — TOUCHDOWN, BILLS. Singletary seals the deal for the Bills’ opening drive, scoring a touchdown on fourth down. The drive lasted almost seven minutes with 13 plays. Bills 7, Chiefs. 0.

6:46 p.m. — Singletary runs for his third first down of the drive, this time for 15 yards.

6:43 p.m. — Josh Allen converts on fourth down after running 10 yards. 

6:40 p.m. — The Bills receive the ball first in the final divisional game in this year’s playoffs. The Bills’ first play results in a first down after Devin Singletary runs 13 yards.

Bills vs. Chiefs start time 

  • Date: Sunday, Jan. 23
  • Time: 6:30 p.m. ET

The Bills vs. Chiefs game will kick off at 6:30 p.m. ET at Arrowhead Stadium in Kansas City, Mo.

What channel is Bills vs. Chiefs on today? 

  • TV channels: CBS
  • Live streams: Paramount+, fuboTV

The Bills vs. Chiefs matchup will be broadcast nationally on CBS with announcers Jim Nantz and Tony Romo on the call and Tracy Wolfson on the sidelines.

For those hoping to stream the matchup, CBS will carry the game on its streaming platform, Paramount+. You can also stream NFL games live online with fuboTV, which offers a free trial.

In Canada, viewers can watch Bills vs. Chiefs with a subscription to DAZN,  which includes every NFL game .

NFL playoff schedule 2022

Divisional round

Saturday, Jan. 22

Matchup Start time TV channel Live stream
Bengals 19, Titans 16 4:30 p.m. ET CBS Paramount+,  fuboTV
49ers 13, Packers 10 8:15 p.m. ET Fox fuboTV

Sunday, Jan. 23

Matchup Start time TV channel Live stream
Rams 30, Buccaneers 27 3 p.m. ET NBC Peacock,  fuboTV
Chiefs 42, Bills 36 (OT) 6:30 p.m. ET CBS Paramount+,  fuboTV

Conference championships

Sunday, Jan. 30

Matchup Start time TV channel Live stream
Bengals vs. Chiefs 3:05 p.m. ET CBS Paramount+, fuboTV
49ers vs. Rams 6:40 p.m. ET Fox Fox Sports app, fuboTV

Super Bowl 56

Sunday, Feb. 13

Matchup Start time TV channel Live stream
Super Bowl 56 6:30 p.m. ET NBC NBC Sports app, fuboTV

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Alzheimer’s and severe COVID-19: Comparing brain damage markers

healthcare professional wearing mask, attending to ICU patient in hospitalShare on Pinterest
Healthcare worker Demetra Ransom comforts a person with COVID-19 at United Memorial Medical Center in Houston, Texas, on December 4, 2020. MARK FELIX/Getty Images
  • A study demonstrated that participants hospitalized with COVID-19 experiencing neurological complications had higher levels of blood proteins or biomarkers associated with neurological damage than people with Alzheimer’s.
  • Increased biomarker levels correlated with COVID-19 severity, mortality risk, and the presence of neurological disorder.
  • Long-term follow-up is necessary to determine if biomarker elevation is associated with an increased risk of developing subsequent neurodegenerative disorders.

COVID-19, the disease that a SARS-CoV-2 infection causes, often brings on mild upper respiratory symptoms. However, some individuals may experience severe illness requiring hospitalization. This can occur due to pneumonia and lung damage causing respiratory failure.

In addition, neurological manifestations commonly occur in people hospitalized with COVID-19. Neurological disorders may include encephalopathy, seizures, stroke, encephalitis, Guillain-Barré syndrome, and acute demyelinating encephalomyelitis.

Researchers at NYU Grossman School of Medicine conducted a study that investigated whether people with COVID-19 experiencing new-onset neurological complications during hospitalization had elevated blood markers indicating neurological damage.

The investigators published study results in the journal Alzheimer’s and Dementia.

Dr. Thomas Wisniewski, M.D., a co-author of the study, professor of neurology, pathology, and psychiatry, and director of both the NYU Alzheimer’s Disease Research Center and the Center for Cognitive Neurology, spoke about the study in an MNT interview.

He explained: “It’s clear that the [SARS-CoV-2] virus has a propensity for inducing vascular damage, targeting in the endothelial cells, and causing disruption of the blood-brain barrier, as well as inducing generalized neuroinflammation. Cytokines like interleukin 6 and interleukin 1 are much elevated in [individuals with COVID-19], and these are cytokines that drive neurodegeneration and Alzheimer’s disease.”

Cytokines are proteins that help the body’s cells to communicate.

Dr. Wisniewski added, “In our study, we became interested in looking at these types of biomarkers, [since these biomarkers] are what we follow in our Alzheimer’s disease research center for looking at the progression of Alzheimer’s-related pathology and other neurodegenerative disorders.”

In an interview with MNT, Jennifer Bramen, Ph.D., a senior research scientist at the Pacific Neuroscience Institute at Providence Saint John’s Health Center in Santa Monica, CA, who was not involved in the study, described the seven biomarkers the study measured:

  • Total tau and pTau181 are indicators of neuron damage. Their levels increase as AD progresses. In AD, abnormal proteins form tangles, blocking the communication between brain cells, she explained.
  • Ubiquitin C-terminal hydrolase L1 (UCHL1) is an enzyme that breaks down unnecessary proteins in brain cells. Brain injury or neurodegenerative diseases such as AD cause levels of UCHL1 to increase.
  • Increased glial fibrillary acidic protein (GFAP) levels indicate damage to the glial cells. Glial cells help maintain the health of brain cells and the blood-brain barrier, which filters toxic substances.
  • Neurofilament light chain (NfL) measures damage to axons of myelinated neurons. The axon is the part of the neuron that conducts electricity, and myelin is the insulation surrounding the neuron.
  • Amyloid-β (Aβ) 40 and 42 are proteins that build up and cause the formation of amyloid plaques in AD, which disrupt brain cell function and communication.
  • Lastly, a person’s pTau181 to Aβ42 ratio may identify early stages of AD.

Investigators also attempted to determine the association of increased biomarkers with rates of discharge to home and in-hospital death rates.

To assess the level of injury, the researchers compared serum biomarker levels of a control group of participants who had “normal” cognition, mild cognitive impairment (MCI), and AD with the biomarkers of people during hospitalization with COVID-19 and new neurological findings.

Researchers conducted a retrospective analysis of participants enrolled in the Study of Neurologic and Psychiatric Events in Acute COVID-19 (SNaP Acute COVID study), which examined serum samples people gave during their hospitalization for COVID-19.

Dr. Wisniewski explained, “We specifically excluded patients who have a preexisting cognitive disorder, any sort of dementia, or mild cognitive impairment, [to prevent clouding of the results].”

The SNaP Acute COVID study was a prospective study of 4,491 participants conducted in four New York hospitals between March 10 and May 20 of 2020, which evaluated the development of new neurological events during acute COVID-19 hospitalization.

The non-COVID control group comprised blood samples from the NYU Alzheimer’s Disease Research Center clinical core cohort banked before January 1, 2020. This was the date of the first reported COVID-19 cases in New York City. The researchers used validated testing tools — version three of the Uniform Data Set and the Clinical Dementia Rating — to stratify the control participants into three subgroups: normal cognitive functioning, MCI, and AD.

The study measured blood markers using an ultrasensitive testing methodology called single-molecule array technology.

The COVID-19 group consisted of 251 participants with a median age of 71. This group was 63{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} male. There were 161 participants in the control group with a median age of 71. Participants in the control group were 35{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} male.

The most common neurological complications included toxic metabolic encephalopathy (TME) in 63{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of participants and brain injury due to reduced oxygen or blood flow in 46{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809}.

The severity of COVID-19 correlated most strongly with total tau, pTau181, and NfL levels.

Higher GFAP and pTau181/Aβ-42 levels were associated with a significantly increased risk of death during hospitalization. Results showed that elevated levels of total tau, NfL, and GFAP corresponded to decreased discharge-to-home rates.

Those participants with COVID-19 who experienced new neurological events during hospitalization had significantly higher total tau, pTau181, NfL, and UCHL1, with the highest levels occurring in those with TME. The participants with COVID-19 had a 179{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} percent higher NfL, 73{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} higher GFAP, and 13{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} higher UCHL1 level than the AD group.

Dr. Wisniewski commented:

“In the study, we found very marked elevations of these seven biomarkers, indicating [the] significant presence of neurodegeneration, neuronal death, and gliosis. With marked neurodegeneration, neuroinflammation, and — at least at one time point — elevation of Alzheimer’s disease biomarkers, each […] correlated with the presence of neurological disease and the severity of infection as well as the outcome.”

Dr. Braman stated: “One limitation is that [the study] is only looking at hospitalized patients, so it’s still not clear if these biomarkers might be present in patients with less severe COVID-19 symptoms. Future research would be [needed] to understand how long lasting these effects are and how much they link up with actual cognitive deficits.”

Dr. Wisniewski agreed:

“We have been following these patients for 6 months and one year […] and there was the persistence of cognitive dysfunction [in up to 50{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of these folks]. Hence, it’s important to follow this up. [P]erhaps biomarker findings speak of an increased risk of subsequent neurodegenerative disorders in this population.”

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Thierry Mugler, legendary French fashion designer, dies at 73

French fashion designer Thierry Mugler is pictured here on October 10, 2014 in Friedrichstadt-Palace theater in Berlin.

Legendary French trend designer Manfred Thierry Mugler, known for his dramatic and avant garde styles, died Sunday. He was 73. 

Mugler’s death was declared on his formal Instagram account. “RIP. We are devastated to announce the passing of Mr Manfred Thierry Mugler on Sunday January 23rd 2022,” the announcement mentioned. “May possibly his soul Rest In Peace.” 

No cause of demise was provided. 

The designer’s vogue property also verified the information of Mugler’s death “with deep disappointment” Sunday evening. “A visionary whose creativeness as a couturier, perfumer and graphic-maker empowered persons all over the environment to be bolder and dream greater each day,” the Home of Mugler official Instagram account mentioned. 

United states of america These days has arrived at out to Mugler’s reps for comment.

The celebrated vogue designer’s death comes five times just after the Jan. 18 death of André Leon Talley, the visionary previous creative director of Vogue magazine.

RIP André Leon Talley: Manner sector icon and former innovative director of Vogue, dead at 73

Related:Kim Kardashian describes Mugler’s generation at 2019 Achieved Gala

Born December 21, 1948, in Strasbourg, France, Mugler launched his 1st style assortment called “Café de Paris” in 1973. 

In an job interview with WWD journal printed in September, Mugler spoke about his early beginnings in fashion. “… All I desired to do was this really pure, Parisian silhouette: the tiny black fit, the trenchcoat, the black dress, the siren dress,” Mugler mentioned. 

“I did the first nude entire body-aware costume. Nobody was performing nude at that time. My very first ready-to-have on line was termed Café de Paris, and it was all about a very specific, streamlined silhouette, very strongly motivated by dance.” 

In this photo taken on October 3, 1999, French fashion designer Thierry Mugler is cheered by his models and the audience after the presentation of his Spring/Summer 2000 ready-to-wear collection in Paris. French designer Thierry Mugler, who reigned over fashion in the 1980s, died on January 23, 2022 at the age of 73.

Mugler became internationally acknowledged as a designer in the course of the 1980s and 1990s. He intended 1 of the most renowned robes of the 90s, which appeared in the 1993 romance/drama “Indecent Proposal,” starring Demi Moore. Moore donned the timeless black slice-out velvet backless amount while giving the basic line: “The dress is for sale, I’m not.” 

Mugler retired from fashion in 2002, but in additional current years, the designer’s iconic appears have been worn by significant-profile entertainers including Woman Gaga, Kim Kardashian, Cardi B, David Bowie, Miley Cyrus, Nicole Kidman, Bella Hadid and Diana Ross. 

Ross shared a photo of her and Mugler on Twitter, producing, “I will miss you Thierry Mugler this was a fantastic time in our lives.”

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What are the benefits of buying cosmetic jars wholesale?

What are the benefits of buying cosmetic jars wholesale?

What are the benefits of buying cosmetic jars wholesale?

Cosmetic jars have become quite innovative over the years. However, the most important thing for most people is to find and use jars that can hold cosmetics for a long time without any problems. In essence, preservation is key. Well, in case you are planning to buy these jars, then the idea of getting them on wholesale should be top of your priorities. After all, cosmetic jars wholesale offer several key benefits and here are some of them:

Save big

One thing you can be sure about wholesale cosmetic jars is the fact that they will always sell for a lower price compared to retail jars. In fact, wholesale can allow you to save as much as 30{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} or more in your final purchase. So, if your budget is tight or perhaps you just want to get yourself a bargain, going for wholesale jars is highly advised.

You don’t have to buy a lot

When people think about cosmetic jars wholesale, they often assume that a person needs to purchase hundreds or thousands of jars to qualify. This is not true in fact, most wholesalers will let you buy a few jars for your daily use and still enjoy super savings in the long run. But if you still need to buy hundreds or thousands of bottles, it is still okay to do it.

Enjoy free shipping

A lot of cosmetic jars wholesale suppliers will often have free shipping. Also, even if the supplier does not necessarily specialise in wholesale, when you order in bulk, you will qualify for certain price breaks, most of which include free shipping to your destination. This will help you save a lot of money in the end on your apothecary jars.

Enjoy good quality

A lot of people typically buy cosmetic jars once and they use them for a long time. If you can be able to get a reliable supplier, then it will be much easier to secure your long-term high-quality supply of apothecary jars. This in particular applies to people who are buying wholesale apothecary jars to use in commercial establishments like salons. A decent supplier guarantees a bulk supply of top-quality jars and in the end, you can even build a long term relationship with that company.

Buying cosmetic jars in wholesale offers so many immense benefits. The good news is that you don’t even have to order thousands or hundreds of these bottles to qualify for the advantages.