Is the COVID-19 pandemic linked to a rise in blood pressure levels?

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New research examines trends in blood pressure during the pandemic. Aleks_G/Getty Images
  • Governments enacted emergency measures in response to the COVID-19 pandemic.
  • These measures significantly altered people’s behavior.
  • In a new study, researchers wanted to see if there was a link between these changes in behavior and effects on people’s blood pressure.
  • The researchers found blood pressure increased during the pandemic compared with previous, non-pandemic years.

In a new study, researchers have found that blood pressure increased in adults in the United States during the pandemic compared with previous, non-pandemic years.

The research, published in the journal Circulation, makes clear that the health effects of the pandemic include not just the COVID-19 disease but also other, indirect health issues.

According to the Centers for Disease Control and Prevention (CDC), blood pressure describes the pressure blood exerts against a person’s arterial walls.

Doctors measure blood pressure at two points: when a person’s heart is pumping, known as systolic blood pressure, and when a person’s heart is resting between beats, known as diastolic blood pressure.

If a person has high blood pressure, also known as hypertension, they are at a greater risk of stroke or heart disease. Hypertension can also damage a person’s liver, eyes, and brain.

The CDC state that 47{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of U.S. adults have hypertension, and in 2019 hypertension was the primary or contributing cause of more than 500,000 deaths.

A person can help maintain healthy blood pressure levels by eating a diet low in salt and high in fruit and vegetables, exercising regularly, avoiding smoking, and limiting alcohol intake.

However, the COVID-19 pandemic significantly disrupted people’s behavior and access to regular medical care.

Researchers are interested to see if this disruption had an effect on people’s blood pressure levels.

To look at blood pressure levels during the pandemic relative to previous years, a group of scientists studied data from an employee wellness program in the U.S covering 2018–2020.

This involved 464,585 participants, 53.5{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of whom were women, with an average age of 45.7 years in 2018. The paper offered no information regarding the racial or ethnic makeup of the participants.

The scientists compared blood pressure levels before the pandemic in 2018, 2019, and until March of 2020, when most U.S. states gave stay-at-home orders. They then compared these levels with those recorded from April–December 2020 during the pandemic.

The researchers found that before the pandemic, there was no significant change in blood pressure between years.

However, each month during the pandemic, blood pressure increased by an average of 1.1 to 2.5 millimeters of mercury (mmHg) for systolic blood pressure and 0.14 to 0.53 mmHg for diastolic blood pressure. This was the case for both women and men of different ages.

Women, on average, had greater increases for both systolic and diastolic blood pressure. Older participants had greater systolic blood pressure increases, whereas younger participants had greater diastolic blood pressure increases.

Speaking to Medical News Today, Dr. Luke Laffin, co-director of the Center for Blood Pressure Disorders at the Cleveland Clinic in Ohio and the study’s lead author, said that “[d]ietary indiscretion, lack of exercise, central obesity, excessive alcohol consumption, and not taking prescribed blood pressure medications can all drive high blood pressure.”

“Other research demonstrates that lifestyle habits like excessive alcohol intake worsened during the pandemic, so it is not surprising that a blood pressure elevation followed.”

“We also know that patients hesitated to see their doctor, particularly in the early part of the pandemic, and that may have contributed to increased blood pressures,” said Dr. Laffin.

Prof. Matthew Bailey, who leads hypertension and renal research at the Centre for Cardiovascular Science at the University of Edinburgh, Scotland, and was not involved in the study, told MNT that the findings were significant and had global implications.

“This paper has examined almost half a million people and clearly shows that the societal changes [and] restrictions imposed in response to the pandemic have increased blood pressure. The effect is particularly large in women, and there is also an unanticipated increase in young people.”

“A rise in blood pressure of this size increases the risk of debilitating heart attack or stroke. For individuals and their families, cardiovascular disease can be devastating. [F]or governments, these conditions are costly to treat and manage. Health budgets are already overstretched.”

“This study is based in the U.S. but is relevant globally. It provides an early warning signal that poor cardiovascular health might be a big problem a few years down the line,” said Prof. Bailey.

Dr. Tarek Antonios, a senior lecturer in physiological medicine at St George’s, University of London in the United Kingdom, and not involved in the study, told MNT the findings were not unexpected.

“I was not surprised when I saw this article. I am concerned about hypertension and the epidemic. If you put the two together — the COVID-19 epidemic and hypertension — there are certain different avenues [that connect] them.”

“The first one is the increased anxiety levels among the population. Lots of people lost their jobs, they became redundant, lost their businesses, and they lost income — all of this created a lot of stress and anxiety, and that can increase blood pressure. So this is one possible explanation.”

“The second is during the lockdown, there were no open gyms, no one was going out for running or sports, and many people — including some of my patients — put on a significant amount of weight. And once you put on weight, your blood pressure goes up as well.”

“The third point is that people are sitting at home most of the time, they order takeaways, and takeaways are full of salt, and therefore people have increased their salt intake. So there is a lot of stuff that may not be directly related to COVID-19, but [was] indirectly affected by this epidemic.”

“Some patients also found it very difficult to get in touch with their GPs and get a refill of their prescriptions. Some stopped taking their medications, and that also increased their blood pressure levels. [T]his is something we need to give information about to patients — that it is very important that they don’t stop the tablets.”

“Many of my patients have bought blood pressure machines so that they can monitor their own blood pressure and make sure that their blood pressure is well-controlled. This is my advice to most patients: get their own blood pressure machines and start measuring their blood pressure at home.”

Prof. Bailey said that he thought low-level stress and low quality sleep might be key factors in the increase in blood pressure.

“High blood pressure is caused by […] lifestyle [and] environmental factors that were difficult to avoid during pandemic restrictions. Many of us ate too much comfort food — high in salt, fat, and sugar — had limited capacity to exercise, and may have indulged in other […] habits such as drinking too much alcohol or smoking. Of these, the study was only able to discount weight gain itself.”

“I think a major factor is chronic low-level stress and poor sleep patterns. I think this will emerge as a big factor once more studies are done,” said Prof. Bailey.

Speaking to MNT, Dr. Helen Flaherty, head of health promotion and education at Heart Research UK and not involved in the study, also agreed that a range of factors may be at play when accounting for the increase in blood pressure.

“As a result of the pandemic, many people have seen a change to their usual lifestyle habits which, in many cases, can impact negatively on their blood pressure and cardiovascular health.”

“People working from home may be less physically active as they miss out on their usual walk to work or a trip to the gym. Physical activity may also be restricted where people are isolated at home due to the pandemic. In addition, changes to dietary habits, such as buying more takeaway foods, which may be higher in salt, can also contribute to raised blood pressure.”

“Many people have found the pandemic to be stressful and long-term stress is also associated with an increase in blood pressure, as well as behaviors that can increase blood pressure, such as smoking and alcohol consumption,” explained Dr. Flaherty.

As well as possible indirect factors that might account for the rise in blood pressure, Dr. Antonios highlighted that there could be more direct causes.

“The disease itself may cause high blood pressure because of the interaction with certain molecules like the angiotensin-converting enzyme receptors. Moreover, many of my patients called to tell me that once they got the vaccines — especially the first dose — their blood pressure went very high, and they ended up in A&E and casualty with systolic blood pressure exceeding 200 in some of them.”

“What is also interesting is that for many of [my patients], the blood pressure did not settle down and remained high — not as high as 200, but higher than it was before. I am doing some research now to look at the effects of vaccination on blood pressure. And I have at least nine patients who had the same reaction: [their] blood pressure went up, and they ended up in casualty at St George’s [hospital].”

“Since then, there have been two publications — one from Lausanne in Switzerland and the second from Italy — that describe exactly this. Especially with the BioNTech vaccine, the blood pressure goes very high. What we don’t know is why this happens and why it does not settle down,” said Dr. Antonios.

Dr. Antonios also said there could be a connection between long COVID and hypertension. However, this required more research.

“What we don’t know so far is if hypertension is part of the long COVID syndrome. Most papers and reviews have not included hypertension [as part of long COVID]. They have included, for example, chest problems, myocarditis, thromboembolic phenomena, or even diabetes, but hypertension is not yet part of this long COVID syndrome, which we don’t know much about.”

Dr. Laffin said researchers should continue monitoring blood pressure levels:

“It is going to be very important to identify if blood pressure elevations persisted throughout 2021, given that vaccination became more widespread and individuals started returning to see their medical provider. I think it is unlikely that we’ll see a decline to pre-pandemic levels until the current pandemic ends.”

Crucially, there are limitations to the generalizability of the study’s findings. In the U.S., Black adults consistently exhibit significantly higher rates of hypertension, for example, compared with their white counterparts. However, the present study did not characterize blood pressure based on race or ethnicity. This is an important point that researchers should further evaluate during the pandemic.

Fortunately, there are many things a person can do to try and maintain healthy blood pressure levels.

Prof. Bailey said: “I try to make sure I eat well and sleep well and have goals for regular exercise. Using mindfulness or breathing apps can be a really good way to unplug for a few minutes in the day. It’s a great idea to get your blood pressure measured — know your numbers — and to remember to keep taking the medicine if you have high blood pressure.”

“High blood pressure increases your risk of having a heart attack or stroke. However, many people are unaware that they have high blood pressure as there are usually no symptoms. It is important to have your blood pressure checked regularly. Ideal blood pressure is below 120/80 mmHg,” Dr. Flaherty told us.

“To maintain healthy blood pressure, it is important to maintain a healthy weight by eating a healthy diet and getting plenty of physical activity. Eating a diet that is not too high in salt also helps to avoid raised blood pressure. Keep an eye on food labels and avoid foods that have a high salt content, such as salted nuts and potato chips.”

“Limit your alcohol intake to no more than the recommended amounts — in the U.K. this is no more than 14 units of alcohol a week, spread out over 3 or more days.”

“Physical activity can help to reduce your blood pressure, and adults should aim to do 150 minutes of moderate-intensity activity — for example, brisk walking — or 75 minutes of vigorous-intensity activity — for example, running — each week.”

Could herbs and spices lower blood pressure?

  • Large blood tension, or hypertension, raises the possibility of coronary heart condition and stroke, both of which are main leads to of death in the United States.
  • Nourishment advice on how to decreased blood stress generally features utilizing herbs and spices alternatively than salt to taste foods. However, authorities know little about the wellbeing added benefits of herbs and spices.
  • A new randomized managed demo implies that a diet plan rich in herbs and spices may perhaps minimize blood stress in men and women at chance of cardiovascular condition.

In accordance to the Centers for Disorder Regulate and Avoidance (CDC), approximately 50 {cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of grown ups in the U.S. have hypertension.

Untreated hypertension will increase the hazard of cardiovascular sickness, these as coronary heart assault, stroke, heart failure, kidney disease, eyesight reduction, and hurt to blood vessels.

Nutritional assistance on reducing blood stress consists of lessening salt ingestion. The Dietary Suggestions for Americans suggest working with herbs and spices rather of salt to taste foodstuff.

Specialists know a lot less about the overall health outcomes of herbs and spices than they do about all those of salt. Nonetheless, some experiments have demonstrated that herbs and spices can lessen lipemia — the extra of lipids in the blood — hyperglycemia, and oxidative pressure.

To dig a little further, scientists at Pennsylvania Condition College a short while ago done a randomized managed demo investigating the result of for a longer time-term use of herbs and spices on danger things for cardiovascular condition.

They located that a better level of herbs and spices in foodstuff decreased 24-hour blood stress readings.

The findings show up in the American Journal of Scientific Nourishment.

Prof. Penny Kris-Etherton, 1 of the guide authors of the examine, informed Professional medical Information Today, “Indeed, the blood force-lowering consequences of herbs and spices in an common Western diet plan were being astonishing to me.”

“We [already know] about the results of quite a few way of living variables, specifically dietary components, that can boost blood tension — these as sodium, alcohol, and caffeine — and other people that can minimize blood strain, these kinds of as potassium, magnesium, and calcium, […] excess weight loss, physical exercise, and some nutritional vitamins, which includes folate and vitamin D when consumption is low, but the blood pressure-lowering outcomes of herbs and spices are new!”

“In terms of herbs and spices,” she ongoing, “there has not been a clinical demo showing benefits on blood tension lowering until eventually our study.”

A overall of 71 contributors aged 30–75 yrs joined the analyze. All members experienced one or far more risk aspects for cardiovascular condition and had obese or weight problems.

After the contributors fasted for 12 hours, the researchers designed baseline assessments. These involved height, fat, waistline circumference, a fasting blood sample, and vascular tests.

Vascular screening integrated central and peripheral blood tension and arterial stiffness measurements. The members also wore a blood force watch for 24 several hours.

The researchers then randomly assigned the individuals to 1 of three teams. Every single team would take in one of a few weight loss plans: a low spice diet program, a reasonably spiced diet, or a significant spice eating plan. These eating plans included a day by day consumption of .5 grams (g), 3.3 g, and 6.6 g of herbs and spices, respectively.

The intention was to incorporate herbs and spices into a eating plan that was representative of the common U.S. diet plan. The extra herbs and spices provided cinnamon, turmeric, and oregano.

The participants adopted their respective diet programs for 4 months, with a 2-week break in concerning. At the stop of every diet regime time period, the members returned for follow-up assessments. A complete of 63 people today done the analyze.

The review showed that the high spice diet program tended to make improvements to 24-hour blood strain readings, when compared with the medium and very low spice meal plans.

The scientists did not notice any result of the weight loss plans on reduced-density lipoprotein cholesterol, clinic-calculated blood tension, markers of glycemia, vascular function, or oxidative strain.

Having said that, they say that 24-hour blood tension readings are a stronger predictor of cardiovascular demise than clinic blood stress measurement.

The authors imagine that the examine could possibly have been far too short for vascular reworking to happen, which might demonstrate why they did not see any influence on arterial stiffness.

They also note that the dosages of herbs and spices might not be sufficient to overturn the metabolic results of an unhealthy qualifications diet. For that reason, they are unable to endorse expanding consumption of herbs and spices by itself in the context of a very poor excellent diet program to decrease the possibility of cardiovascular ailment.

Furthermore, because every working day of the menu bundled various quantities of the 24 herbs and spices, exposure was not regular. As herbs and spices do not keep in the procedure for pretty prolonged, the food items eaten during the times closest to screening may possibly have influenced the outcomes a lot more strongly.

Dr. Simon Steenson, a nourishment scientist at the British Nourishment Foundation, explained to MNT, “This research implies there could be probable reward in terms of blood stress reduction for together with extra herbs and spices in just our food plan.”

“However,” he ongoing, “the results witnessed were small and not significant in between all levels of consumption. Whilst the authors recommend there may well be some advantage to including herbs and spices in a suboptimal diet regime, clearly, the purpose from a public wellbeing place of see need to be to enhance dietary styles in line with evidence-based mostly advice on eating plan and overall health.”

Prof. Kris-Etherton mentioned to MNT, “It will be significant to assess the outcomes of personal spices on blood strain and to fully grasp the mechanism[s] by which each and every lowers blood stress.”

“It would also be fascinating to assess the results of herbs and spices on the microbiome and assess whether or not the effects of herbs and spices on [blood pressure] are modulated by any variations in the gut microbiome.”

“Beyond scientific demo study, studies are required to appraise productive education systems that educate use of herbs and spices in a healthful dietary pattern that is decreased in sodium, saturated extra fat, and included sugar on food plan top quality and medical endpoints, these as danger aspects for continual diseases.”

Dr. Steenson concluded:

“It is vital to observe that whilst the goal of this examine was to look at the normal American diet plan, we require major shifts in average dietary patterns to make our taking in behaviors much healthier and far more sustainable. When certain foodstuff or substances may possibly have a tiny advantage by yourself, we require to encourage a shift to much healthier ingesting throughout the board.”