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Who develops ‘super immunity’?

Photo of someone receiving a COVID-19 vaccination in The Netherlands taken from aboveShare on Pinterest
A new study investigates so-known as super immunity. Nicolas Economou/NurPhoto through Getty Photographs
  • A latest analyze investigated how the immune technique responds following each SARS-CoV-2 an infection and COVID-19 vaccination.
  • The findings counsel that “hybrid immunity,” resulting from vaccination and an infection, requires the strongest immune response. Some get in touch with it “super immunity.”
  • Total, the purchase of vaccination and an infection built minimal distinction to the attainment of this immunity.

With so numerous individuals, which includes absolutely vaccinated men and women, contracting SARS-CoV-2, researchers want to fully grasp how the combination of vaccination and the infection could affect the immune response.

A new research from Oregon Health and Science College (OHSU), which appears in Science Immunology, explores this concern.

It also investigates the antibody response of folks who were unvaccinated at the time of the an infection but later on grew to become vaccinated.

Considering the fact that COVID-19 was 1st detected in late 2019, a lot more than 360 million individuals have contracted SARS-CoV-2, and just about 5.6 million persons have died, globally.

To combat the pandemic, medical teams have administered an amazing 9.6 billion doses of COVID-19 vaccines so significantly.

As anticipated, as costs of vaccination increase, health care professionals sign-up more breakthrough bacterial infections. This variety of an infection requires a entirely vaccinated individual contracting SARS-CoV-2.

When compared with unvaccinated people today, vaccinated people are considerably less probable to create severe illness or die from COVID-19, the Centers for Disorder Control and Avoidance (CDC) report.

“The probability of obtaining breakthrough infections is large for the reason that there is so a lot virus all over us ideal now,” describes Dr. Fikadu Tafesse, co-senior creator of the analyze and an assistant professor of molecular microbiology and immunology at OHSU.

Experts know that SARS-CoV-2 infection presents a diploma of natural immunity, but there is much discussion about how very long this immunity lasts and how productive it is, when compared with the immunity that vaccination provides.

Specified the current significant costs of breakthrough infections, and specified that some men and women are obtaining vaccinated immediately after acquiring contracted the virus, researchers are curious about how these factors impact the body’s immune response.

The authors of the recent review gathered information from 104 contributors, whom they divided into a few types:

  1. fully vaccinated individuals with a breakthrough SARS-CoV-2 an infection
  2. men and women who had a SARS-CoV-2 infection followed by vaccination
  3. absolutely vaccinated people today with no background of a SARS-CoV-2 an infection

The initial group experienced 31 individuals, the 2nd also experienced 31, and the third experienced 42 participants.

The researchers took blood samples from the contributors and uncovered them to various dwell SARS-CoV-2 viruses. They then calculated the immune response.

The researchers determined that it did not matter whether an individual obtained the vaccine very first or contracted the infection 1st. The immune system responded similarly.

“It can make no change no matter whether you get contaminated and then vaccinated or if you get vaccinated and then a breakthrough infection,” says Dr. Tafesse. “In both circumstance, you will get a definitely, really sturdy immune reaction — surprisingly significant.”

The researchers also identified that the “hybrid” immune response is powerful regardless of age, while the reaction from only the vaccine tends to minimize with age.

The workforce uncovered that the hybrid immune reaction is robust, regardless of how people today received this immunity. However, it is still greatest to get vaccinated first and get actions to avert the infection.

“We position ourselves better by receiving vaccinated,” Dr. Tafesse clarifies. “And if the virus comes, we’ll get a milder scenario and close up with this super immunity.”

In a put up on Twitter, Dr. Shane Crotty, a professor of virology at the Vaccine Discovery Division of the La Jolla Institute for Immunology, addressed hybrid immunity:

“It’s the most effective immunity you can get, but I wouldn’t think of hybrid immunity as remaining a pressure area that can wholly prevent it, no make any difference what.”

The scientists believe that that this so-termed tremendous immunity could signal that the COVID-19 pandemic will develop into endemic.

“These outcomes, with each other with our preceding do the job, level to a time when SARS-CoV-2 may well grow to be a generally mild endemic an infection, like a seasonal respiratory tract an infection, as an alternative of a around the globe pandemic,” states co-senior author Dr. Marcel Curlin.

Dr. Curlin is an affiliate professor of medication at the OHSU Faculty of Drugs and director of OHSU Occupational Well being.

Dr. William Messer, a senior co-writer of the paper, spoke with Medical Information Now about the research. Dr. Messer is an assistant professor of molecular microbiology and immunology and medication at OHSU.

“As for the change towards ending the pandemic — I assume this is a piece in the puzzle, even a fairly big piece, but there are many items to factor in, not minimum the ongoing evolution of the virus alone,” Dr. Messer described.

Dr. Messer additional that the scientists “hope to examine this ‘super immunity’ influence for Omicron, precisely inquiring the question whether an infection with Omicron has related boosting properties.”

For reside updates on the most up-to-date developments concerning COVID-19, click on below.

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EFIC1 and Azerion Today Proceed With the Completion of the Business Combination

The initially day of listing and trading on Euronext Amsterdam under the new name
“Azerion Group N.V.” and ticker symbol “AZRN” anticipated to be 2 February 2022

General public disclosure of inside of info in accordance with report 17(1) of the Regulation (EU) No 596/2014 on industry abuse (Marketplace Abuse Regulation)

AMSTERDAM, Feb. 01, 2022 (World NEWSWIRE) — Reference is created to the joint push release issued by European FinTech IPO Enterprise 1 B.V. (“EFIC1”), a unique objective acquisition company (SPAC) mentioned on Euronext Amsterdam (symbol: EFIC1 and EFICW), and Azerion Holding B.V. (“Azerion”), a superior-growth, EBITDA successful, digital leisure and media enterprise, on 13 December 2021 asserting that they have attained a definitive settlement to build a company mix (the “Business Combination”) pursuant to which EFIC1 will receive 100{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of the issued and superb share cash of Azerion (the “Business Blend Agreement”).

In link with the Business enterprise Mixture, EFIC1 and Azerion also entered into subscription agreements with specific traders (which include sure sponsors of EFIC1 or sure affiliate marketers of EFIC1’s sponsors), pursuant to which this kind of investors agreed to order and subscribe for common shares in EFIC1 for an aggregate quantity of EUR 23.15 million (the “Subscription Agreements”).

The Organization Mixture Settlement as well as the Membership Agreements consist of sure (waivable) customary completion problems.

EFIC1, Azerion and Azerion’s shareholders have now decided that all ailments less than every single of the Subscription Agreements and the Small business Mixture Agreement have possibly been fulfilled or waived and will proceed with the completion of the sponsors and co-traders placement and the Organization Mix.

The Business enterprise Blend is expected to be finished afterwards now, 1 February 2022, with the remaining structuring methods as approved by EFIC1’s shareholders at the extraordinary meeting of shareholders held on 31 January 2022 (this kind of as the conversion of the lawful kind of EFIC1 into a restricted organization (naamloze vennootschap)) taking area all through the morning of 2 February 2022. The put together entity will additionally be renamed “Azerion Team N.V.” and its ordinary shares and warrants are predicted to commence investing on Euronext Amsterdam on 2 February 2022 less than the ticker symbols “AZRN” and “AZRNW”, respectively.

Push AND Trader Information and facts EFIC1

Push contacts: Marion Banide (banide@hague.corporation +31 () 62 144 1396) and Matthias Goldbeck
(matthias.goldbeck@ccounselors.com +49 () 172 842 7007).
Trader contacts: ir@efic1.com or +31 (20) 240 4240.

DISCLAIMER

This push launch is for info purposes only. The information and facts contained in this press release does not purport to be entire or comprehensive and, in unique, does not contain all the facts that should really be regarded as regarding the proposed company mix involving European FinTech IPO Corporation 1 B.V. (“EFIC1”) and Azerion Keeping B.V. (“Azerion”) pursuant to a small business mix arrangement concerning EFIC1, Azerion and Azerion’s shareholders (the “Business Combination”) and is not supposed to form the foundation of any investment selection or any other conclusion in regard of the Business enterprise Mix. No reliance might be put by any person for any function on the facts contained in this press launch or its precision, fairness or completeness.

No reliance may well be placed by any particular person for any intent on the facts contained in this push launch or its precision, fairness or completeness. EFIC1 will not be held liable for any reduction or damages of any nature ensuing from making use of, trusting or acting on facts presented. This push launch does not constitute, and should not be construed as, an give to promote or a solicitation of any offer to purchase the standard shares and/or warrants of EFIC1 and is not a suggestion to have interaction in any investment decision routines.

This press release may incorporate specified forward-wanting statements, which are primarily based on latest expectations and projections with respect to foreseeable future occasions and converse only as of the day hereof (“Forward-hunting Statements”). By their nature, Ahead-looking Statements are matter to recognized and not known hazards, uncertainties, assumptions and other elements due to the fact they relate to activities and depend on conditions that will take place in the long run irrespective of whether or not outdoors the control of EFIC1. Such variables may trigger precise results, general performance or developments to vary materially from individuals expressed or implied by this sort of Forward-wanting Statements. No assurances can be specified that the Forward-hunting Statements will be realised. No representation or warranty is created that any of these Ahead-hunting Statements will appear to go or that any believed consequence will be reached. Accordingly, no undue reliance ought to be positioned on any Forward-searching Statements.

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A Rivian comedown after R1T, stock euphoria

“The plant, which will inevitably use more than 7,500 workers, represents a important up coming step as Rivian scales aggressively toward larger-capacity output for our long term era of items,” the enterprise mentioned.

But the tide immediately turned on fresh new struggles that underscore the extended highway ahead for the newbie builder of shopper EVs and commercial delivery vans.

In late December, Rivian claimed it will delay deliveries of the R1T and the R1S SUV with prolonged-assortment batteries until finally 2023. The delay will allow the enterprise to prioritize the much more well-liked regular-assortment cars, CEO RJ Scaringe explained in a letter to clients posted on Reddit.

“The subsequent various months will continue being a steep climb as we carry on to ramp up our operations,” Scaringe explained.

Early in the new year, Stellantis announced that Amazon will be its initial shopper for the new Ram ProMaster battery-electric van, beginning in 2023. That poses opposition to Rivian, which counts Amazon as its largest purchaser with an original buy of 100,000 supply vans by 2025.

Very last 7 days, Rivian disclosed 2021 generation of 1,015 automobiles — limited of its 1,200 objective. It also verified the departure of COO Rod Copes. Rivian informed the Wall Road Journal, which very first reported the information, that Copes’ departure had been prepared.

In the aftermath of the modern setbacks, Rivian’s stock selling price was hovering around its IPO price tag of $78 previous 7 days following soaring as large as $172 in mid-November.

While the the latest situations have been a comedown from the submit-IPO pleasure, it unquestionably wasn’t surprising, presented the volatility of EV startups. Tesla was close to individual bankruptcy a few a long time in the past but then became the very first automaker with $1 trillion current market benefit in October.

“I feel Rivian will however be Ok in the lengthy operate, but these are excellent illustrations of how swiftly a new automaker’s fortunes can swing, or at the very least show up to swing,” explained Karl Brauer, executive analyst at iSeeCars.com.

Rivian reported in a letter to shareholders Dec. 16 that it experienced 71,000 buyer orders for the R1T and R1S, in addition to the Amazon buy for its EDV vans. Rivian said its planned ability of 200,000 cars a yr at its existing factory in Typical, Unwell., will be bolstered by the Georgia plant in the in close proximity to long term.

“Just after a 12-year journey of having our technique and choices completely ready for purchaser deliveries, it has been amazingly satisfying to see the exhilaration and enthusiasm for what we are creating,” mentioned the shareholder letter, which accompanied the third-quarter earnings report.

Stephanie Brinley, principal analyst at IHS Markit, mentioned Rivian faces a extended highway forward but seems to be prepared.

The Amazon order with Stellantis won’t automatically threaten the EV startup considering the fact that Amazon will want numerous partners to reach its zero-emissions aims, Brinley claimed. And solid customer desire in the Rivian model would seem unaffected by new corporation news.

“As Rivian scales and ramps up output, it may perhaps continue to see some bumps in the street, but the business does look ready to weather conditions people bumps,” she explained. “Cracking the vehicle marketplace to become a quantity producer will just take time.”

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Today’s coronavirus news: Ontario reporting 2,983 people hospitalized with COVID-19, 583 in ICU; Boris Johnson says sorry after ‘partygate’ report released

The latest coronavirus news from Canada and around the world Monday. This file will be updated throughout the day. Web links to longer stories if available.

6:15 p.m.: The Star’s Rosie Dimanno has touched down in Beijing for the upcoming 2022 Summer Olympics. But as the columnist writes, “never before … have I ever felt so alien and menacing a presence, not to mention barely tolerated.”

Read the full column here.

6:02 p.m.: U.S. Defense Secretary Lloyd Austin, in letters to seven governors, is reaffirming the need for members of their states’ Army and Air National Guards to get the mandatory COVID-19 vaccine or lose their Guard status.

In nearly identical letters signed late last week, Austin tells the governors that the virus “takes our service members out of the fight, temporarily or permanently, and jeopardizes our ability to meet mission requirements,” according to copies obtained Monday by The Associated Press.

The letters, which have not been publicly released, come as the military services begin to ramp up the number of active-duty troops being discharged for refusing the vaccine. Nearly 600 Marines, airmen and sailors have been thrown out of the military or dismissed from entry-level training at boot camps as of last week.

Two of the letters — to Alaska and Texas state leaders — note that they have an ongoing lawsuit over the vaccine and that, Austin said, limited his abililty to comment further on their concerns.

Texas, Oklahoma and Alaska filed lawsuits challenging the military’s vaccine mandate, but a federal judge has already rejected the Oklahoma challenge. The Alaska governor was one of five Republican state leaders who sent a letter to Austin asking him not to enforce the mandate on National Guard troops. The other four were governors from Wyoming, Mississippi, Iowa and Nebraska.

The latest letters were to those five governors along with Idaho and Texas.

According to the Centers for Disease Control and Prevention, nearly 87 per cent of the U.S. population age 18 or older has gotten at least one shot.

5:30 p.m.: Joe Rogan has apologized after being critized for hosting two guests in recent weeks on his popular podcast who espoused dangerous COVID misinformation.

In his apology episode, Rogan also thanked his listeners who have enjoyed his podcast and said he would “try harder to get people with differing opinions on right afterward” and “do my best to make sure I have researched these topics, the controversial ones in particular, and have all the pertinent facts at hand before I discuss them.”

Read the full story by the Star’s Alessia Passifiume here.

5:22 p.m.: Saskatchewan Premier Scott Moe says Saskatchewan’s proof of vaccination against COVID-19 has run its course, but he won’t commit to removing the requirement before the public health order expires at the end of the month.

He says the government doesn’t make decisions overnight, but discusses them with health officials who provide input.

On the weekend, Moe said in a letter in which he supported a truck convoy against mandatory vaccines that Saskatchewan would remove the public health order in the “not-too-distant” future.

Since then, the premier has said proof of vaccination or a negative test no longer help with preventing transmission of COVID-19.

5:00 p.m.: With leaders such as Ontario Premier Doug Ford and Toronto chief medical officer of health Dr. Eileen de Villa calling for Canadians to learn to “live with” COVID-19, what does that exactly mean?

The Star’s Jenna Moon spoke with several doctors to try to map out a way forward past the pandemic.

4:47 p.m. Prime Minister Justin Trudeau says he will neither meet with nor be intimidated by the convoy of Canadians he says spent the last few days harassing local businesses, waving Nazi flags and stealing food from the homeless.

Speaking to Canadians from isolation after testing positive for COVID-19 Monday, Trudeau said “freedom of expression, assembly and association are cornerstones of democracy.”

“But Nazi symbolism, racist imagery, and desecration of war memorials are not,” he said. “It is an insult to memory and truth. Hate can never be the answer.”

Trudeau and his family were moved to an undisclosed location Saturday as thousands of people converged all over Ottawa, including some near his official residence on the grounds of Rideau Hall.

3:40 p.m. For nearly two years, Canadians have faced rolling restrictions on public life due to the ongoing threat of COVID-19. As the Omicron wave begins to wane in the province, politicians and doctors alike are beginning to envision a world where we move beyond emergency measures and live alongside the virus.

Ontario Premier Doug Ford said Friday that the province needs to learn to “live with” COVID-19. That thought was echoed the same day by Toronto’s medical officer of health Dr. Eileen de Villa, who said a mix of vaccinations, masking, distancing and ventilation will help lessen the risk of severe flare-ups of the virus as Toronto moves away from a “COVID-zero” approach to handling the pandemic. As of Monday, some restrictions placed on indoor dining, gyms and movie theatres have been lifted, though they will only be able to operate at 50 per cent of their regular capacity.

Meanwhile, a study released Monday has shown just how far the virus spread in Canada as a result of the highly-contagious Omicron variant: One in every five households has seen at least one case of COVID since the beginning of December. The same study found that more than half of respondents support an end to restrictions.

But what does “living with” COVID-19 look like? As Dr. Nelson Lee, interim director of the Dalla Lana Institute for Pandemics, told the Star, it’s not so much about living with the virus as it is about overcoming it.

Read the full story from the Star’s Jenna Moon.

3:32 p.m. The Quebec government loosened more COVID-19 restrictions Monday, permitting small private indoor gatherings and reopening restaurant dining rooms at half capacity, after it imposed an abrupt lockdown over the holidays.

After lifting the provincial curfew and allowing in-person classes to resume on Jan. 17, the government is permitting restaurants to host no more than four people at one table, or two households, and forcing them to close at midnight.

3:12 p.m. The prime minister says the government will introduce legislation today to continue providing as many rapid tests as possible to the provinces and territories.

Justin Trudeau made the announcement today during a news conference that addressed the Parliament Hill protest against government-imposed COVID-19 measures.

The bill was added to the order paper on Saturday, ahead of MPs returning to Parliament Monday.

Liberal House leader Mark Holland said at a news conference today that Bill C-10 would accelerate the funding and provision of rapid tests because there is “great” need for them.

2:30 p.m. A truck blockade snarling border traffic between Montana and Alberta is causing political and police tensions to ratchet up.

It began over the weekend alongside the “Freedom Convoy” that made its way into Ottawa, bringing thousands of protesters upset with public health measures and the federal government.

The blockade of trucks in southern Alberta near the village of Coutts is made up of a line of vehicles that backed up traffic for about two kilometres on Sunday, according to local reports.

The Star’s Kieran Leavitt has the latest.

1:55 p.m. The Duke and Duchess of Sussex have “concerns” about how Spotify has allowed and promoted the spread of COVID-19 misinformation on its platform.

Prince Harry and Meghan, who inked an exclusive multiyear partnership with the service in December 2020, said Sunday that they are pressing Spotify to take more care about the rhetoric spread on its airwaves.

“Since the inception of Archewell, we have worked to address the real-time global misinformation crisis. Hundreds of millions of people are affected by the serious harms of rampant mis- and disinformation every day,” a representative for their foundation said in a statement Sunday.

1:45 p.m. As promised by the province, a number of COVID-19 restrictions in Ontario were lifted on Monday.

As of 12:01 a.m., several limits on social gatherings, and indoor and outdoor capacities were eased, as part of a “cautious” three-stage reopening plan released earlier this month. The plan consists of three consecutive phases of public health measures being eased, with 21 days between each phase.

This comes just after Premier Doug Ford said Ontarians need to learn to live with COVID-19 in an interview Friday.

A change in social gathering limits, a return to indoor dining and gyms reopening are all part of the loosened restrictions that are now in place.

Read the full story from the Star’s Akrit Michael

1:30 p.m. It was back to class Monday for students in New Brunswick and Prince Edward Island as a result of eased COVID-19 restrictions.

Both provinces have installed portable HEPA filters in classrooms without mechanical ventilation systems.

Heather Mullen, president of the P.E.I. Home and School Federation, says it’s important for students to be back in school and benefit from social interaction with their classmates.

She says while some parents were nervous about sending their children back today, she believes it’s safe because all students and school staff on the Island needed two negative rapid tests from the weekend, and all are wearing new high-quality masks.

High school students in New Brunswick head back to class Wednesday, while P.E.I. high school students return Thursday.

Last week, New Brunswick Education Minister Dominic Cardy thanked teachers and parents for their efforts during the extended period of online learning that resulted from the Omicron wave of the pandemic.

1:15 p.m. The mayor of a village in southern Alberta says there will be no mail and some students have not gone to school because of a truck convoy that has blockaded a highway at a busy U.S. border crossing as part of a protest against vaccine mandates.

Mayor Jim Willett says he’s angry and frustrated because about 100 trucks lined up on Highway 4 are preventing a mail truck and a school bus from entering Coutts, Alta.

The convoy is one of many in Canadian towns and cities on the weekend that coincided with truckers and their supporters meeting on Parliament Hill in Ottawa to protesting the federal government’s COVID-19 measures.

Willett says he understands freedom to protest, but he adds the Alberta government needs to act to allow the movement of goods and services near the border, where only foot traffic has been able to get through.

1 p.m. Ontario is reporting 583 people in ICU due to COVID-19 and 2,983 in hospital overall testing positive for COVID-19, according to its latest report released Monday morning.

This marks the fifth straight day hospitalization numbers due to COVID have shown a downward trend. It is important to note that all hospitals don’t report COVID numbers on the weekend.

Around 22.6 per cent of the province’s 2,343 adult ICU beds remain available for new patients.

Read the full story from the Star’s Akrit Michael

12:37 p.m. Quebec is taking its first steps on Monday toward reopening the province after partially shutting down over the holidays due to record-high hospitalizations.

Premier François Legault announced plans last week to gradually loosen public health restrictions as the COVID-19 situation began to improve.

Beginning Monday, restaurant dining rooms can open at half capacity, with no more than four people or two different households at a table, and they must close by midnight.

The changes come as Quebec is today reporting 33 additional deaths attributed to COVID-19.

The Health Department says 2,888 people are hospitalized, a drop of seven patients from the previous day, and 223 people are in intensive care, a decline of 10.

Quebec is reporting 2,423 new COVID-19 cases, but authorities have warned that number is not reflective of the actual situation because PCR testing has been limited to certain higher-risk groups.

12:12 p.m. (updated) In a Monday presser, Prime Minister Justin Trudeau, who tested postive for COVID-19, thanks the truckers who are doing hard jobs and are on the road right now. He says they have continued to step up to put food on the shelves and support Canadians with necessary medication.

He says almost 90 per cent are doing the right thing. “We thank you deeply.”

Trudeau says the behaviour in Ottawa this weekend does not represent hard-working truckers.

“This is not the story of our pandemic, of our people,” Trudeau says. “…there is no place in our country to threats and hatred.”

Trudeau says this has to stop.

12:10 p.m. Premier Doug Ford on truckers’ protest: “I was extremely disturbed …to see some individuals desecrate our most sacred monuments and wave swastikas and other symbols of hate and intolerance this weekend. That has no place in Ontario or Canada. Not now. Not ever.”

Ford also said: “Today, Ontario is beginning to ease some public health measures, the first step in returning to normal. All Ontarians are united in their desire to put this pandemic behind us and return to the life we knew before COVID-19.”

11:35 a.m. Moderna announced Monday that U.S. health regulators granted full approval to its COVID-19 vaccine, a shot that’s been given to tens of millions of Americans since its emergency authorization over a year ago.

The action by the Food and Drug Administration means the agency has completed the same rigorous, time-consuming review of Moderna’s shot as dozens of other long-established vaccines.

The decision was bolstered by real-world evidence from the more than 200 million doses administered in the U.S. since the FDA cleared the shot in December 2020. The FDA granted full approval of Pfizer’s vaccine last August.

11:17 a.m. British Prime Minister Boris Johnson apologized Monday for lockdown-flouting parties in Downing Street — but insisted that he and his government can be trusted.

Johnson told lawmakers in the House of Commons that he would make changes to the way the government is run in the wake of the “partygate” scandal.

“I get it and I will fix it,” he said.

He spoke after senior civil servant Sue Gray found that gatherings by the prime minister and his staff when Britain was under coronavirus restrictions represent a “serious failure” to observe the standards expected of government.

10:16 a.m. Ontario is reporting 2,983 people hospitalized with COVID-19 and 583 in the ICU. The province is reporting at least 3,043 new cases.

Note that not all hospitals report on weekends. In Ontario, 30,649,731 vaccine doses have been administered; 91.9 per cent of Ontarians 12+ have one dose and 89.2 per cent have two doses, according to tweets from Health Minister Christine Elliott.

10:12 a.m. Prime Minister Justin Trudeau says he has tested positive for COVID-19.

Trudeau posted on Twitter that he got the positive test result Monday morning. He has been in isolation since last Wednesday when he said that he’d had a positive contact.

CP reported that the contact was one of his children, but the PMO had not identified which of his children had contracted the virus.

“I’m feeling fine — and I’ll continue to work remotely this week while following public health guidelines. Everyone, please get vaccinated and get boosted,” Trudeau tweeted.

Read the full story from the Star’s Tonda MacCharles

9:51 a.m. Prime Minister Justin Trudeau says he’s tested positive for COVID-19.

In a statement on Twitter, Trudeau says: “I’m feeling fine – and I’ll continue to work remotely this week while following public health guidelines. Everyone, please get vaccinated and get boosted.”

9:47 a.m. An investigation says lockdown-breaching parties by Prime Minister Boris Johnson and his staff represent a “serious failure” to observe the standards expected of government.

Senior civil servant Sue Gray concluded that “there were failures of leadership and judgment” in the government and “some of the events should not have been allowed to take place.

The findings are part of what Gray’s office calls an “update” on her investigation, rather than a full report. Major parts of her findings have been withheld at the request of the police, who have launched a criminal investigation into the most serious alleged breaches of coronavirus rules.

The cuts have led opponents to accuse Johnson of a whitewash.

Johnson is due to make a statement on the findings in the House of Commons later Monday.

9:15 a.m. Los Angeles County’s nursing homes have observed an extraordinary increase in coronavirus case rates during the Omicron surge — reaching levels exceeding even last winter’s wave — but that unprecedented torrent of infections hasn’t been matched by a record-high number of daily COVID-19 deaths, county health data show.

The county has instead observed a relatively small increase in daily COVID-19 deaths at nursing homes during the omicron surge, officials said. And new daily coronavirus cases have already started to drop.

As of mid-January, L.A. County was tallying a daily COVID-19 death rate of 20 fatalities for every 100,000 nursing home residents. That’s about one-fifth of the peak of last winter’s surge, and roughly one-fourth the rate of the pandemic‘s early days in spring 2020, according to figures presented by L.A. County Public Health Director Barbara Ferrer.

8:55 a.m. Hamilton school boards say they are struggling to put teachers in classrooms as systems report average staff absences of more than 1,000 a day.

Schools reopened to in-person learning Jan. 19 for the first time since before the winter break amid a rapidly spreading Omicron wave of COVID.

“It has been challenging,” said Hamilton-Wentworth Catholic District School Board chair Pat Daly. “The absenteeism rates have been higher than pre-pandemic. It was a challenge before the pandemic, so it’s been exacerbated now.”

The Catholic board reported average daily vacancy rates of about 504 — or 12 per cent — among staff, which includes educators, as well as administrative and custodial staff, and 212 among teachers in the first three days back to school.

8:30 a.m. Grocery prices are skyrocketing. Inflation is at a 30-year high. Interest rate hikes are on the horizon. And the housing market shows no signs of cooling.

And yet your salary hasn’t changed — maybe even in years.

Canadians are noticing their dollar isn’t stretching as far these days, and wondering when their pay will catch up.

At the same time, a tight labour market means companies are doing more, such as raising wages on new job postings, to try to attract and retain talent.

Read the full story from the Star’s Rosa Saba

8:12 a.m. One of Peel’s highly visited COVID-19 vaccination clinics is back to allow those with busy daytime schedules to receive the first, second or booster dose.

The Doses After Dark clinic is set to run at Brampton’s Save Max Sports Centre on Feb. 5 and at Mississauga’s Rockwood Mall on Feb. 12, both from 1 p.m. till midnight.

Appointments are now live and can be booked online through the provincial website or on Peel Region’s COVID-19 website.

“Our previous Doses after Dark events were very well received so, please book as this special event and these late evening appointments will go quickly,” said the region’s medical officer of health, Dr. Lawrence Loh.

7:10 a.m. Prime Minister Boris Johnson has received a long-awaited report from an investigation into lockdown-breaching government parties, the government said Monday.

The Cabinet Office said senior civil servant Sue Gray “has provided an update on her investigations to the Prime Minister.”

Johnson’s office has promised the report will be published “swiftly,” and that the prime minister will address Parliament about its findings.

But Monday’s “update” is unlikely to tell the full story. Some of Gray’s findings are being withheld because of a separate police investigation into whether some of the gatherings broke COVID-19 laws.

Allegations that the prime minister and his staff flouted restrictions imposed on the country to curb the spread of the coronavirus have caused public anger and led some Conservative lawmakers to call for Johnson’s resignation.

6:20 a.m.: Gyms, movie theatres and museums in Ontario will also be able to reopen Monday, after having been shut down for the last several weeks.

Perhaps more than anything, business owners are hoping this is the last time they’re forced to close, after having gone through waves of lockdowns and reopenings, then back into lockdown, since the COVID-19 pandemic began in March 2020.

They’re also left to wonder: Will the customers come back?

Read the full story from the Star’s Josh Rubin.

6:20 a.m.: A senior Hong Kong government official has resigned after attending a large birthday party that fueled complaints of double standards by authorities enforcing strict Covid-control measures.

Home Affairs Secretary Caspar Tsui handed his resignation to Hong Kong Chief Executive Carrie Lam on Monday and will leave the post immediately, he said in a statement. Lam is set to hold a briefing at 3 p.m., at which more details are expected.

“As one of the principal officials taking the lead in the anti-epidemic fight, I have not set the best example during the recent outbreak,” he said in the statement. Tsui added that he had “behaved in an inappropriate manner when all efforts should have been devoted to controlling the spread of the virus.”

His resignation marks the first time a government official has left a post after flouting pandemic guidance, and comes as the city’s strict zero-tolerance approach to Covid is strained by an omicron variant-fueled surge.

Lam launched a disciplinary probe after Tsui and some 30 officials were found to be among about 250 attendees at a party for the local representative of a mainland Chinese economic development agency on Jan. 3. Days earlier, the government had urged the public to avoid large gatherings due to the global spread of omicron.

6:20 a.m.: New Zealand Prime Minister Jacinda Ardern said Monday she has tested negative for the coronavirus after coming into close contact with an infected person on a commercial flight.

Ardern had been isolating since late Saturday after the Jan. 22 exposure first came to light. She intends to continuing isolating through Tuesday to complete a 10-day health requirement. She has had no symptoms.

The exposure occurred on a flight from the town of Kerikeri to New Zealand’s largest city, Auckland. Health officials listed a dozen flights as exposure events late Saturday, possibly indicating infections among flight crews.

Ardern and Gov.-General Cindy Kiro, who is also isolating while awaiting a second test, were in the Northland region to do some filming ahead of New Zealand’s national day, Waitangi Day, on Feb. 6.

New Zealand has managed to stamp out or contain the virus for much of the pandemic, and has reported just 52 virus deaths among its population of 5 million. But an outbreak of the omicron variant is starting to take hold and is expected to rapidly grow over the coming weeks.

About 77{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of New Zealanders are fully vaccinated, according to Our World in Data. That figure rises to 93{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of those aged 12 and over, according to New Zealand officials.

6:19 a.m.: Tokyo has launched a mass inoculation drive for COVID-19 booster shots at a temporary center operated by the military as Japan tries to speed up delayed third jabs to counter surging infections.

Japan began administering booster shots to medical workers in December, but has only provided such inoculations to 2.7 per cent of the population after delaying a decision to cut the interval between the first two coronavirus shots and a booster to six months from the initial eight.

Demand for the shots is intense: Online reservations that started on Friday resulted in all slots for about 4,300 doses to be given at the center this week being filled within 9 minutes. The center is providing the vaccine made by Moderna, Inc.

On a smaller scale, people 65 and older can get booster shots elsewhere.

The center run by the Self-Defense Force in downtown Tokyo reopened Monday after closing down in late November. It will be vaccinating about 720 people aged 18 or older per day this week, ramping up to more than 2,000 a day next month. Another military-run center will begin booster shots next week in Osaka.

6:18 a.m.: People across Asia prepared Monday for muted Lunar New Year celebrations amid concerns over the coronavirus and virulent Omicron variant, even as increasing vaccination rates raised hopes that the Year of the Tiger might bring life back closer to normal.

The Lunar New Year is the most important annual holiday in China and falls on Tuesday, Feb. 1. Each year is named after one of twelve signs of the Chinese zodiac in a repeating cycle. The Year of the Tiger follows the Year of the Ox.

This will be the third new year in a row celebrated in the shadow of the pandemic. It was two days before the holiday in 2020 that China locked down Wuhan — a city of 11 million people — following the detection of the coronavirus there.

Some 85{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of Chinese are now fully vaccinated, according to Our World in Data, and more Chinese have been travelling domestically this year, despite government warnings. Many people prepare to celebrate by buying red lanterns and other decorations for their homes, and food to mark the beginning of a new year.

6:18 a.m.: Legislators plan to return to the House of Commons on Monday morning as a Parliament Hill protest against government-imposed COVID-19 measures enters its third full day.

Many of the horn-honking demonstrators who brought Ottawa to a near standstill on the weekend showed no signs of budging as parliamentarians, businesses and school administrators were left wondering when the usual rhythm of the frazzled national capital would resume.

Alexandra Maheux, a spokeswoman for government House leader Mark Holland, said the ongoing protest is not interfering with parliamentary business.

“We have important work to accomplish for Canadians in Parliament, and we’re looking forward to getting this done and delivering results,” Maheux said late Sunday.

She noted that MPs have the flexibility to work in a hybrid House in this sitting, which remains in effect until June, to help curb the spread of COVID-19.

“Some MPs will be in the chamber on Monday and beyond, and others will participate virtually,” Maheux said.

A memo circulated Sunday by Patrick McDonell, the House sergeant-at-arms, said security plans were being developed to ensure personal safety.

Holland has scheduled a morning news conference in Parliament’s West Block to discuss the sitting.

He is likely to face questions about the roaming crowds and ear-splitting truck horns outside on Wellington Street, and just how long the protest will be allowed to continue.

6:17 a.m.: A study published Monday in the Canadian Medical Association Journal found that adult COVID-19 patients with disabilities had 36 per cent longer hospital stays and a 77 per cent increased risk of readmission within 30 days.

Advocate Sandi Bell, who has a mobility disability and vision impairment, said it’s important to see studies highlighting the challenges that COVID-19 has caused for many people with disabilities.

“There is a definite demand for data, because a lot of people just don’t know about the daily barriers,” said Bell, a member of the Board of Directors of ARCH Disability Law Centre.

“COVID has been the most isolating situation that one could imagine for people with disabilities.”

Researchers at the University of Toronto and Unity Health Toronto looked at 1,279 patients — 22.3 per cent of whom had a recorded disability — who were hospitalized for COVID-19 at seven nearby hospitals from January through November 2020.

They found that patients with traumatic brain injury, intellectual or developmental disabilities, and multiple disabilities had the highest risks for poor COVID-19 outcomes.

The longer hospital stays and increased rates of readmission for people with disabilities persisted even after accounting for age and other factors that might explain differences.

6:16 a.m.: On the East Coast, schools were set to reopen to in-person learning in New Brunswick and Prince Edward Island Monday, with added safety measures in place.

6:16 a.m.: Quebec is taking its first steps today to reopen the province after partially shutting down over the holidays due to record-high hospitalizations.

Premier François Legault announced plans last week to gradually loosen public health restrictions as the COVID-19 situation has improved somewhat.

Restaurant dining rooms can open at half capacity today, with no more than four people or two different households at a table. Closing time is set for midnight, with last call at 11 p.m.

Private indoor gatherings of up to four people, or two family bubbles, are also permitted.

Extracurricular sports can resume in elementary and high schools, CEGEPs and universities, with the mandatory vaccine passport for students 13 and over.

The second phase of Quebec’s plan to ease restrictions is set for a week from now, with places of worship, entertainment and sports venues allowed to reopen at limited capacity on Feb. 7.

6:15 a.m.: Ontario’s restaurants, gyms and theatres will welcome patrons back today for the first time in nearly a month.

It’s the first step in the province’s plan to gradually ease public health restrictions meant to curb the spread of COVID-19.

Restaurant dining rooms, gyms and cinemas will reopen at half capacity today after being shuttered on Jan. 5 due to the rapid spread of the Omicron variant of the coronavirus.

Larger venues will also reopen with capacity limited to 50 per cent or 500 people — whichever is fewer.

Limits on indoor gatherings will increase from five people to 10, while the cap on outdoor gatherings will go from 10 to 25.

The province plans to ease COVID-19 measures further on Feb. 21.

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49ers vs. Rams final score, results: LA headed to Super Bowl, Kupp finishes with 2 TDs

The Los Angeles Rams are headed to Super Bowl 56 after defeating the 49ers 20-17 in the NFC Championship on Sunday night. 

The Rams defied the odds by making a second half comeback after trailing by 10 points heading into the half. The Rams shut the 49ers out in the second half, scoring 13 unanswered points. A pick off Jimmy Garoppolo sealed the deal for the Rams with just over a minute remaining in the game.

Cooper Kupp (142) and Odell Beckham Jr. (113) both finished with over 100 receiving yards. This is the first time two Rams players have finished with at least 100 receiving yards this season. The last time the Rams did this in the playoffs was during the 2004 wild-card game (Torry Holt and Kevin Curtis), when they were the St. Louis Rams, according to ESPN Stats & Info .

Kupp scored the Rams’ only two touchdowns of the night. Deebo Samuel scored the longest touchdown of the night, though, with a 44-yard scoring play in the second quarter. Samuel finishes his season with an average of 10 yards per catch, which leads wide receivers in the league this season. George Kittle scored the 49ers’ other touchdown of the game.

The Rams won’t have to travel for the Super Bowl on Feb. 13 as their home stadium, SoFi Stadium, will be hosting the biggest game of the year. The Rams will face the AFC champions, the Bengals.

Sporting News tracked live scoring updates and highlights from 49ers vs. Rams on Sunday. Read below for complete results from the 2022 NFC Championship game.

MORE: Watch NFL games live with fuboTV (free trial)

49ers vs. Rams score

  Q1 Q2 Q3 Q4 F
49ers 0 10 7 0 17
Rams 0 7 0 13 20

49ers vs. Rams live updates, highlights from NFC championship

(All times Eastern.)

End of fourth quarter: Rams 20, 49ers 17

9:35 p.m. — INTERCEPTION, RAMS. Travin Howard intercepts the pass intended for Hasty after the ball jumped into the air from an Aaron Donald block. Howard ran to the 13-yard line with just over a minute remaining.

9:34 p.m. — Not a great start to the 49ers’ drive after Gaines knocks away Garoppolo’s pass intended for JaMycal Hasty.

9:32 p.m. — FIELD GOAL, RAMS. The Rams take the lead after Gay makes a 30-yard field goal. They have now scored 13 unanswered points. 1:46 remains in the NFC Championship. Rams 20, 49ers 17.

9:30 p.m. —  Samson Ebukam and Bosa take down Stafford for a loss of seven yards on second down. This moves the Rams to a 3rd-&-18 attempt with under two minutes to play.

9:25 p.m. — Kupp makes another huge play, this time for 25 yards. This is his sixth converted third down of the game. The Rams are on the 49ers’ 12-yard line.

9:24 p.m. — Blanton continues to step up after Higbee was ruled out of the game this half. Blanton completes an 8-yard first down for the Rams.

9:21 p.m. — The 49ers go three-and-out thanks to a delay of game.

9:14 p.m. — FIELD GOAL, RAMS. Fred Warner takes down Sony Michel on third down to force the Rams to settle for a field goal. Gay makes the 40-yard field goal to tie the game. Rams 17, 49ers 17.

9:12 p.m. — Kupp continues to keep the Rams alive after he advances 16 yards to the 49ers’ 25-yard line.

9:09 p.m. —  Jaquiski Tartt almost picks off Stafford, but he drops the ball. The pass is ruled as incomplete.

9:02 p.m. — The Rams force the 49ers to a fourth down after Gaines and A’Shawn Robinson take down Kyle Juszczyk. Sean McVay uses his last challenge to review this play. The play stands as the runner being down on contact ruling.

8:59 p.m. — The 49ers open their drive with a 21-yard gain from Elijah Mitchell. 

8:55 p.m. — TOUCHDOWN, RAMS. Kupp catches an 11-yard touchdown pass from Stafford to make it a three-point game. 49ers 17, Rams 14.

End of third quarter: 49ers 17, Rams 7

8:50 p.m. — Kendall Blanton advances 20 yards to the 49ers’ 20-yard line to finish out the third quarter.

8:47 p.m. — On the first play of the Rams drive, Azeez Al-Shaair was flagged for unsportsmanlike conduct for something he said to Kupp after the play. This penalty moves the Rams up 15 yards.

8:42 p.m. — TOUCHDOWN, 49ERS. Kittle catches a 16-yard touchdown pass for Garoppolo. This was Kittle’s first touchdown in six games. 49ers 17, Rams 7.

8:40 p.m. — Jauan Jennings makes his biggest play of the game, fighting for an 11-yard first down. 

8:38 p.m. — Samuel runs 14 yards to put the 49ers on the Rams’ 26-yard line.

8:37 p.m. — Aiyuk catches a 13-yard pass on third down to keep the 49ers’ drive alive.

8:30 p.m. — On 4th-&-1, Stafford attempts to get the first down but was ruled short. The Rams challenged the call, but the call stands.

8:27 p.m. — Beckham Jr. catches two first down passes in a row, one for 13 yards and another for 26 yards.

8:21 p.m. — Garoppolo has two incomplete passes in a row to force the 49ers to punt.

8:18 p.m. — Another Rams penalty gives the 49ers a new set of downs after Ramsey was flagged for illegal contact.

8:15 p.m. — The 49ers get a first down thanks to a neutral zone infraction penalty on Greg Gaines.

8:13 p.m. — Garoppolo is nearly picked by Jalen Ramsey on his first throw of the second half.

End of second quarter: 49ers 10, Rams 7

7:58 p.m. — FIELD GOAL, 49ERS. Robbie Gould makes the 38-yard field goal attempt to end the first half. The 49ers head into the locker room on top, and they will receive the ball in the second half. 49ers 10, Rams 7.

7:56 p.m. — Aiyuk continues to make big plays, this time for 13 yards. The 49ers stop the clock with 20 seconds left of the half on the Rams’ 24-yard line.

7:54 p.m. — Kittle makes his first catch of the game for 11 yards. The 49ers make it to Rams territory on this play.

7:47 p.m. — Matt Gay’s 54-yard field goal attempt finishes wide right, so the Rams end their drive with no points.

7:43 p.m. — Stafford throws a big pass to Ben Skowronek in the end zone, but the pass is incomplete. The Rams remain on the 49ers’ 38-yard line.

7:38 p.m. — Beckham Jr. grabs a 13-yard pass from Stafford on third down. The Rams are on their own 37-yard line.

7:33 p.m. — TOUCHDOWN, 49ERS. Deebo Samuel scores a 44-yard touchdown to tie the game. Unlike the Rams’ drive, the 49ers only took five plays to score. 49ers 7, Rams 7.

7:31 p.m. — Aiyuk nearly made a long touchdown run, but he stepped out of bounds after 31 yards on the Rams’ 42-yard line. Regardless, a huge first down for the 49ers.

7:25 p.m. — TOUCHDOWN, RAMS. Kupp catches a 16-yard pass from Stafford for a Rams touchdown. The Rams’ drive took up 18 plays in 97 yards, which is statistically their best drive of the year. The extra point is good, too. Rams 7, 49ers 0.

7:24 p.m. — Nick Bosa sacks Stafford for a loss of five yards on first down.

7:23 p.m. — Kupp catches a 15-yard pass from Stafford on the Rams’ 15th play of the drive. They are on the 49ers’ 13-yard line.

7:20 p.m. — Tyler Higbee and Cam Akers are both questionable to return to the game.

7:18 p.m. — Stafford runs 14 yards for a big Rams first down. 

7:14 p.m. — Beckham Jr. gets the Rams a much needed first down to keep their drive alive. They are on their own 43-yard line.

End of first quarter: Rams 0, 49ers 0

7:02 p.m. — The 49ers made it to the Rams’ 40-yard line, but decided not to attempt a field goal. They punt back to the Rams on fourth down.

6:59 p.m. — Brandon Aiyuk advances 13 yards for a 49ers first down, their first of the game.

6:56 p.m. — INTERCEPTION, 49ERS. Matthew Stafford’s pass to Kupp was tipped off and caught by Jimmie Ward in the end zone. Ward ran to the 23-yard line.

6:53 p.m. — Tyler Higbee, Odell Beckham Jr. and Cam Akers complete consecutive first downs to put the Rams in 1st-&-Goal territory on the 8-yard line.

6:51 p.m. — Cooper Kupp delivers the first first down of the game after advancing 17 yards.

6:46 p.m. — The 49ers also go three-and-out after Jimmy Garoppolo’s pass to George Kittle is incomplete.

6:44 p.m. — The Rams quickly go three-and-out to start the game.

6:42 p.m. — Michael Buffer starts off the game with his iconic “Let’s get ready to rumble!” phrase as the Rams receive the kickoff.

49ers vs. Rams start time 

  • Date: Sunday, Jan. 30
  • Time: 6:30 p.m. ET, 3:30 p.m. PT

The 49ers vs. Rams game will kick off at 6:30 p.m. ET at SoFi Stadium in Inglewood, Cali. 

What channel is 49ers vs. Rams on today? 

The 49ers vs. Rams matchup will be broadcast nationally on Fox with announcers Joe Buck and Troy Aikman on the call and Erin Andrews on the sidelines.

You can stream NFL games live online with fuboTV, which offers a free trial .

In Canada, viewers can watch 49ers vs. Rams with a subscription to DAZN,  which includes every NFL game .

NFL playoff schedule 2022

Conference championships

Sunday, Jan. 30

Matchup Start time TV channel Live stream
Bengals vs. Chiefs 3:05 p.m. ET CBS Paramount+, fuboTV
49ers vs. Rams 6:40 p.m. ET Fox Fox Sports app, fuboTV

Super Bowl 56

Sunday, Feb. 13

Matchup Start time TV channel Live stream
Super Bowl 56 6:30 p.m. ET NBC NBC Sports app, fuboTV