Ultra-processed foods may increase ovarian and brain cancer risk

Ultra-processed foods may increase ovarian and brain cancer risk

Boxes of cake mix, which are considered ultra processed foods, on a packing line in a factory. Share on Pinterest
Consuming ultra processed foods has been linked to many negative health consequences. Andy Sacks/Getty Images
  • For many years, scientists have linked a healthy diet to a lowered risk for certain diseases.
  • Researchers from Imperial College London found that eating ultra-processed foods increases a person’s risk for developing cancer overall, specifically ovarian and brain cancers.
  • Scientists also found eating those foods heightens a person’s risk of dying from all cancers, especially ovarian and breast cancers.

Doctors have known for some time now that what we eat has a direct effect on our overall health.

The body requires specific nutrients to perform its routine tasks. And a healthy diet is linked to lowering a person’s risk for certain diseases, including cardiovascular disease, type 2 diabetes, and cancer, as well as promoting better mental health.

Now, researchers from Imperial College London say eating ultra-processed foods increases a person’s risk for developing all cancers, specifically ovarian and brain cancers. And these foods also heighten a person’s risk of dying from cancers, especially ovarian and breast cancers.

The study was recently published in the journal eClinical Medicine.

Ultra-processed foods make up the fourth category of the NOVA food classification system.

According to this classification system, a food is considered ultra-processed if it is:

  • an industrial-made food with five or more ingredients
  • made entirely or mostly from substances extracted from foods, such as oils, fats, sugars, and starches
  • includes food substances not normally found in culinary preparations, like hydrogenated oils and modified starches
  • features additives whose main purpose is to imitate aspects of natural foods such as flavors, colors, and emulsifiers

Examples of ultra-processed foods include:

  • sodas and “energy” or sports drinks
  • packaged cookies
  • candies
  • pre-prepared pizza and packaged meats
  • sweetened and flavored yogurts
  • “instant” soups and other mixes
  • sweetened juices
  • baked goods made with hydrogenated vegetable fat, emulsifiers, and other additives

Previous research shows eating ultra-processed foods increases a person’s obesity risk and can accelerate a person’s biological aging.

Additionally, consuming ultra-processed foods has been linked to a higher risk of heart disease, colorectal cancer, dementia, and all-cause mortality.

For this study, researchers used U.K. Biobank records to analyze the diets of 200,000 middle-aged adults. Scientists reviewed participants’ health over a 10-year time span, looking to see if they specifically developed 34 different types of cancer.

Upon review, the research team found people with higher consumption of ultra-processed foods had a greater risk of developing cancer overall.

For every 10{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} increase in ultra-processed food in a person’s diet, that person had a 2{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} increased risk of developing cancer overall.

Additionally, researchers found for every 10{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} increase in ultra-processed food consumption, a person increased their overall cancer death risk by 6{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809}.

“The findings of this study on overall cancer risk are in line with what we know about the importance of a healthy diet in reducing our cancer risk,” Dr. Eszter Vamos, a clinical senior lecturer in the School of Public Health at Imperial College London and lead/senior author of this study told Medical News Today.

“There are many potential ways ultra-processed foods may increase cancer risk, and we need further research to better understand these,” she continued.

“UPFs have poor nutritional quality, are often high in salt, sugar, and unhealthy fats and low in fiber, and promote obesity — which is in itself a risk factor for many types of cancers. Ultra-processed foods may also contain potentially cancer-causing agents such as some controversial food additives, chemicals generated during food processing, and chemicals from packaging.”
— Dr. Eszter Vamos

In addition to overall cancer risk, Dr. Vamos and her team also found for every additional 10{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of ultra-processed foods in the diet, a person increased their risk of developing ovarian cancer by 19{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} and dying from it by 30{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809}.

“This is the first study to assess associations of ultra-processed food consumption with many different types of cancers, including ovarian cancer,” Dr. Vamos explained, adding: “We need further studies from other populations to confirm these findings.”

“However, previous studies suggest that diets high in unhealthy fats and low in vegetables may increase the risk of ovarian cancer,” she said.

“Ultra-processed foods may also promote inflammation that could contribute to cancer risk. Furthermore, some potentially cancer-causing agents such as acrylamide, which may be generated during processing, have been implicated.”
— Dr. Eszter Vamos

Researchers also found for every 10{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} increase in ultra-processed foods in a person’s diet, they raised their breast cancer mortality rate by 16{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809}.

Dr. Parvin Peddi, a medical oncologist and director of Breast Medical Oncology for the Margie Petersen Breast Center at Providence Saint John’s Health Center, California, who was not involved in the study, reiterated that breast cancer has a known correlation with people who are overweight as they can have higher levels of estrogen, which promotes risk breast cancer.

“We do know that people who have ‘unhealthy habits’ like dietary habits, meaning they eat more fatty or they are overweight, and perhaps now ultra-processed foods, have an increased risk of breast cancer.”
— Dr. Parvin Peddi

Medical News Today also spoke with Dr. Steve Vasilev, a board certified integrative gynecologic oncologist and medical director of Integrative Gynecologic Oncology at Providence Saint John’s Health Center and Professor at Saint John’s Cancer Institute in Santa Monica, California, about this study and how ultra-processed foods may cause increased cancer risk. Dr. Vasilev was not involved in the study.

He said the “old school thought” was that various toxins from food processing, as well as added preservatives, lead to genetic mutations that cause cancer.

“That’s probably true to some extent. However, we now know since the Human Genome Project that there’s something called epigenetics, which basically is a study that looks at how genes are turned on and off. For example, if tumor suppressor genes are turned off, it will lead to diseases like cancer,” Dr. Vasilev explained.

However, he said that even if a person is born with the BRCA1 gene that increases their risk for developing breast and ovarian cancer, that does not necessarily mean that person will get one of those diseases. The epigenetics, he explained, leads to that gene being switched on or off in the body.

“So you do have a proactive ability to modulate which genes are turned on and off in your body. And what influences those, some of it is literally the toxins that accumulate from the preservatives and things like that in ultra-processed foods,” Dr. Vasilev added.

So how can people improve their diet to help decrease their cancer risk?

Kate Cohen, a registered dietitian at the Ellison Institute for Transformative Medicine at Providence Saint John’s Health Center in Santa Monica, California, told Medical News Today that while correlation is not causation, medical experts know that around 50{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of cancers can be prevented through diet and lifestyle changes.

“Hence diet is a controllable risk factor that every single one of us can and should take ownership of. You can’t control the physiology of how your body responds to food, but you can control what food you put into your body.”

Cohen, who was not involved in the study, also said this study gives doctors more ammunition to explain, encourage, instruct, and direct patients that a healthy diet has a direct effect on so many different health conditions.

“And now we see that breast, ovarian and other cancers may be on that list. If patients are at higher risk of developing any cancer — man or woman — doctors should be jumping up and down about this, as well as familiarizing patients with the other modifiable risk factors for cancer. We haven’t cured cancer, but we can cure bad diets.”
— Kate Cohen, dietitian

Ultra-processed foods linked to premature, preventable death

Ultra-processed foods linked to premature, preventable death

Packaged biscuits on an assembly line in a factoryShare on Pinterest
A​ new review adds to a expanding physique of exploration displaying that extremely-processed foodstuff can guide to untimely, preventable loss of life. Monty Rakusen/Getty Photos
  • Dietary styles can have an huge affect on health and fitness outcomes.
  • Extremely-processed foodstuff that go via huge amounts of processing can eliminate nutritional benefit and consist of unhealthy aspects.
  • A​ new examine adds to a increasing physique of research showing that extremely-processed food items consumption may perhaps bring about premature, preventable loss of life.

People today have to have vitamins and minerals to survive, but not all food items are the very same or supply the similar dietary price.

Remarkably processed meals are a more prevalent part of diet plans in latest many years, and researchers are nonetheless operating to have an understanding of the complete effects of these nutritional shifts.

A​ current review printed in the American Journal of Preventive Medicine studied how the intake of extremely-processed foodstuff was involved with untimely, preventable dying.

Scientists identified that extremely-processed food items usage may be the attributable bring about of death in a major percentage of fatalities in the Brazillian population.

The conclusions reveal the relevance of reducing the ingestion of ultra-processed meals to reduce health challenges.

Quite a few meals go via a sure quantity of processing so that they do not spoil.

Kimberly Gomer, MS, LDN, a registered dietitian and nourishment specialist, not associated in the review, explained a handful of of the fundamentals of processed food items to Medical Information Nowadays:

“Processing requires a foodstuff in its normal (dwelling-developed) point out and modifications it by introducing salt, sugar, oil, and additives like chemical substances, shades, flavorings, stabilizers, and preservatives. That is why they have an extremely extended shelf everyday living which is beautiful to both equally people and sector.

Extremely-processed foodstuff, nevertheless, go by means of vigorous processing. A number of illustrations of ultra-processed foodstuff include:

  • sodas
  • sweet or savory packaged treats like chips or cookies
  • electricity bars and power drinks
  • prompt soups and other prepared-to-warmth items like pizza or hen nuggets

“Most of these meals have a lengthy record of components located on the ingredient listing of the foodstuff label,” Gomer claimed. “These food items contain — but are not limited to — frozen meals, cakes, cookies, rapid meals, packaged meals, and treats.”

The comprehensive health and fitness implications of ultra-processed food stuff ingestion are however remaining analyzed.

Some research indicates that taking in processed foods decreases diet program quality and boosts the threat for health challenges like significant blood pressure (hypertension), being overweight, and coronary heart sickness.

The new research looked at the variety of deaths in the Brazillian inhabitants and their romantic relationship to the consumption of extremely-processed foods.

Initial, scientists looked at countrywide meals use in Brazil from 2017 to 2018. They then appeared at this data in light of facts on demographics and mortality from 2019.

Depending on age demographics, Brazilians were being obtaining among 13 and 21{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of their overall electricity intake from ultra-processed foods. Researchers seemed at the 541,160 men and women among the ages of 30 and 69 that died in 2019.

Their analysis exhibits that consuming extremely-processed foods was responsible for 10.5{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of all premature deaths in this age demographic.

Scientists further more famous that ultra-processed meals intake was dependable for 21.8{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of all preventable fatalities from non-communicable health conditions.

Examine writer Eduardo A.F. Nilson, ScD, a researcher at the Heart for Epidemiological Investigation in Nourishment and Overall health, University of São Paulo, and Oswaldo Cruz Foundation, Brazil, famous the adhering to highlights of the analysis to MNT:

“It is the initial research that has in fact modeled the overall impression of UPF [ultra-processed food] consumption on fatalities that we are knowledgeable of. The outcomes are substantial firstly simply because the attributable fatalities symbolize a enormous load in conditions of premature deaths from all triggers (57 thousand fatalities depict 21.8{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of the untimely fatalities from preventable non-communicable disorders in Brazil). Additionally, if UPF consumption was kept at the ranges we had a ten years in the past, 21{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of the attributable fatalities could be prevented.”

Based on this details, researchers approximated that reducing down strength consumption from ultra-processed foodstuff by 10-50{cfdf3f5372635aeb15fd3e2aecc7cb5d7150695e02bd72e0a44f1581164ad809} of latest amounts could enormously assist decrease these mortality fees.

“Clinically, the benefits ensure a alter in the paradigm of dietary suggestions toward stopping and managing non-communicable illnesses and to advertising and marketing healthier meal plans in standard,” Dr. Nilson stated.

The analyze provides to a growing body of evidence about the hazards of ultra-processed foods — but it does have some limits that also need to have to be dealt with.

Initial, gurus can’t flawlessly identify the number of fatalities brought on by extremely-processed foodstuff.

The model and examination experienced selected restrictions, such as the danger of confounding and the incapability to account for each and every variable.

Researchers also admit that there is a threat for reverse causation. This was also knowledge collected from just one place, this means that the results may be slightly different in other nations around the world, for greater or even worse.

Eduardo Nilson pointed out that they could operate to apply the facts they collected in other places and other nations around the world:

“We appear ahead to estimating the effect of UPF in other countries, modeling the impacts of different insurance policies and interventions (dietary counseling, UPF taxation, entrance-of-deal labeling, regulation of foods publicity, and many others.), producing designs for particular wellness outcomes (such as cardiovascular illnesses, diabetes, being overweight), incorporating health and fitness financial analyses to the versions and improving upon the models to forecast the impacts of policy interventions.”

It’s unidentified how specifically changes to meals guidelines and tips at nationwide and international degrees could influence the wellbeing of overall populations.

In the meantime, persons can perform with their health professionals and nutrition professionals to reduce down on particular consumption of ultra-processed foods as proper.

“Start by minimizing (inevitably removing) sodas, chips, cookies, fried foods, and junk,” Gomer claimed.

“Replacing junk foodstuff with full food items is important. [Sit] down to foods as an alternative of feeding on on the operate and make the time and energy to get ready healthful foods at household. Problem your self to modest variations. Switch a handful of harmful meals with healthier types.”